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    CG12111 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31796, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG12111provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030050
    Locus tag
    Dmel_CG12111
    See related
    AllianceGenome:FB:FBgn0030050
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG12111
    Summary
    Predicted to enable carbohydrate binding activity and pattern recognition receptor activity. Predicted to be involved in immune response. Predicted to be active in external side of plasma membrane. Is expressed in adult head and organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG12111 in Genome Data Viewer
    Location:
    7F4-7F5; 1-23 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (8570208..8570948, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (8464241..8464981, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Topoisomerase related function 4-1 Neighboring gene antisense RNA:CR46195 Neighboring gene Serine Protease Immune Response Integrator Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Lectin-like proteins in model organisms: implications for evolution of carbohydrate-binding activity. Dodd RB, et al. Glycobiology, 2001 May. PMID 11425795
    2. Comparative genomic analysis of C-type lectin-domain genes in seven holometabolous insect species. Lu Y, et al. Insect Biochem Mol Biol, 2020 Nov. PMID 32841718
    3. Participation of a galactose-specific C-type lectin in Drosophila immunity. Tanji T, et al. Biochem J, 2006 May 15. PMID 16475980, Free PMC Article
    4. The chromosomal high-affinity binding sites for the Drosophila dosage compensation complex. Straub T, et al. PLoS Genet, 2008 Dec. PMID 19079572, Free PMC Article
    5. Reproductive status alters transcriptomic response to infection in female Drosophila melanogaster. Short SM, et al. G3 (Bethesda), 2013 May 20. PMID 23550122, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables carbohydrate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables carbohydrate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables pattern recognition receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12111-PA
    CG12111-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      8570208..8570948 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001272412.1 → NP_001259341.1  uncharacterized protein Dmel_CG12111, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259341.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W3D8
      Conserved Domains (1) summary
      cd00037
      Location:55 → 174
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain

    2. NM_132263.4 → NP_572491.1  uncharacterized protein Dmel_CG12111, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572491.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W3D8
      Related
      FBpp0071176
      Conserved Domains (1) summary
      cd00037
      Location:55 → 174
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W3D8 Q9W3D8

    Gene LinkOut

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