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    su(sable) suppressor of sable [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31012, updated on 9-Dec-2024

    Summary

    Official Symbol
    su(sable)provided by FlyBase
    Official Full Name
    suppressor of sableprovided by FlyBase
    Primary source
    FLYBASE:FBgn0003575
    Locus tag
    Dmel_CG6222
    See related
    AllianceGenome:FB:FBgn0003575
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG6222; Dmel\CG6222; EG:115C2.3; su(s); su-s; su-v; su[2]-s
    Summary
    Enables RNA binding activity. Involved in negative regulation of DNA-templated transcription, elongation and nuclear RNA surveillance. Located in nucleoplasm and polytene chromosome. Colocalizes with euchromatin. Is expressed in salivary gland. Orthologous to several human genes including ZC3H4 (zinc finger CCCH-type containing 4) and ZC3H6 (zinc finger CCCH-type containing 6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See su(sable) in Genome Data Viewer
    Location:
    1B13-1B13; 1-0 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (635890..643760)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (529923..537793)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene MYB binding protein 1a Neighboring gene mir-9372 stem loop Neighboring gene Death related ced-3/Nedd2-like caspase Neighboring gene pseudo Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    colocalizes_with euchromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in polytene chromosome IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    suppressor of sable
    Names
    CG6222-PA
    CG6222-PB
    CG6222-PC
    su(sable)-PA
    su(sable)-PB
    su(sable)-PC
    suppressor-of-sable

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      635890..643760
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_057406.4NP_476754.1  suppressor of sable, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_476754.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O77427, P22293, Q8SYG7
      UniProtKB/TrEMBL
      M9W963
      Related
      FBpp0070115
    2. NM_001297823.1NP_001284752.1  suppressor of sable, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284752.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X2JDA8
    3. NM_001297824.1NP_001284753.1  suppressor of sable, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284753.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O77427, P22293, Q8SYG7
      UniProtKB/TrEMBL
      M9W963