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    TpnC47D Troponin C at 47D [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36195, updated on 17-Dec-2024

    Summary

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    Official Symbol
    TpnC47Dprovided by FlyBase
    Official Full Name
    Troponin C at 47Dprovided by FlyBase
    Primary source
    FLYBASE:FBgn0010423
    Locus tag
    Dmel_CG9073
    See related
    AllianceGenome:FB:FBgn0010423
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE34610; CG9073; Dmel\CG9073; DmTnC2; DmTpnC47D; DmTpnCIb; TnC; TNC; Tnc3; TnC47D; TNC47D; TpnC Ib; TPnC47D; TpnCIb
    Summary
    Predicted to enable calcium ion binding activity and enzyme regulator activity. Predicted to be involved in microtubule cytoskeleton organization. Predicted to be active in cytoplasm. Is expressed in adult head; adult heart; and organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See TpnC47D in Genome Data Viewer
    Location:
    47E5-47E5; 2-64 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (11273845..11275286, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (7161350..7162791, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Cuticular protein 47Ee Neighboring gene Cuticular protein 47Ef Neighboring gene Cuticular protein 47Eg Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila melanogaster genes encoding three troponin-C isoforms and a calmodulin-related protein. Fyrberg C, et al. Biochem Genet, 1994 Apr. PMID 7980384
    2. Expression patterns of the whole troponin C gene repertoire during Drosophila development. Herranz R, et al. Gene Expr Patterns, 2004 Mar. PMID 15161098
    3. Troponin C in different insect muscle types: identification of two isoforms in Lethocerus, Drosophila and Anopheles that are specific to asynchronous flight muscle in the adult insect. Qiu F, et al. Biochem J, 2003 May 1. PMID 12558500, Free PMC Article
    4. Phylogenetic relationship of muscle tissues deduced from superimposition of gene trees. OOta S, et al. Mol Biol Evol, 1999 Jun. PMID 10368962
    5. Noncanonical roles for Tropomyosin during myogenesis. Williams J, et al. Development, 2015 Oct 1. PMID 26293307

    See all (56) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    troponin C at 47D
    Names
    CG9073-PA
    CG9073-PB
    TpnC47D-PA
    TpnC47D-PB
    troponin C

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      11273845..11275286 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299381.1 → NP_001286310.1  troponin C at 47D, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286310.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8E6H7, P47948, Q8IGT2, Q9V5V9
      UniProtKB/TrEMBL
      A0A0B4LF64
      Conserved Domains (1) summary
      COG5126
      Location:8 → 155
      FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

    2. NM_057620.6 → NP_476968.1  troponin C at 47D, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_476968.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8E6H7, P47948, Q8IGT2, Q9V5V9
      UniProtKB/TrEMBL
      A0A0B4LF64
      Related
      FBpp0087280
      Conserved Domains (1) summary
      COG5126
      Location:8 → 155
      FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LF64 A0A0B4LF64
    P47948.2 P47948

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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