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    CG13796 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34051, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG13796provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031939
    Locus tag
    Dmel_CG13796
    See related
    AllianceGenome:FB:FBgn0031939
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13796-PA; CG18590; CT42497; Dmel\CG13796
    Summary
    Predicted to enable glycine:sodium symporter activity and neurotransmitter:sodium symporter activity. Predicted to be involved in glycine import across plasma membrane; neurotransmitter transport; and sodium ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in adult abdomen; adult head; and adult thorax. Human ortholog(s) of this gene implicated in cerebral creatine deficiency syndrome 1 and intellectual disability. Orthologous to several human genes including SLC6A11 (solute carrier family 6 member 11); SLC6A12 (solute carrier family 6 member 12); and SLC6A13 (solute carrier family 6 member 13). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG13796 in Genome Data Viewer
    Location:
    28C2-28C2; 2-28 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (7727157..7732670, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (7727157..7732670, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR46074 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Adult cuticle protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Comparative sequence analysis and tissue localization of members of the SLC6 family of transporters in adult Drosophila melanogaster. Thimgan MS, et al. J Exp Biol, 2006 Sep. PMID 16916974
    2. The invertebrate B(0) system transporter, D. melanogaster NAT1, has unique d-amino acid affinity and mediates gut and brain functions. Miller MM, et al. Insect Biochem Mol Biol, 2008 Oct. PMID 18718864, Free PMC Article
    3. Formation and longevity of chimeric and duplicate genes in Drosophila melanogaster. Rogers RL, et al. Genetics, 2009 Jan. PMID 19015547, Free PMC Article
    4. Chimeric genes as a source of rapid evolution in Drosophila melanogaster. Rogers RL, et al. Mol Biol Evol, 2012 Feb. PMID 21771717, Free PMC Article
    5. A screen for neurotransmitter transporters expressed in the visual system of Drosophila melanogaster identifies three novel genes. Romero-Calderón R, et al. Dev Neurobiol, 2007 Apr. PMID 17443808

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables glycine:sodium symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables neurotransmitter transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables neurotransmitter:sodium symporter activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in amino acid transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in neurotransmitter transport ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    involved_in neurotransmitter transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in sodium ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG13796-PA
    CG13796-PB
    CG13796-PC
    CG13796-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      7727157..7732670 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001144335.2 → NP_001137807.1  uncharacterized protein Dmel_CG13796, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001137807.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IGR3, Q9I7N9
      Conserved Domains (1) summary
      cl00456
      Location:123 → 610
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    2. NM_164767.3 → NP_723309.2  uncharacterized protein Dmel_CG13796, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723309.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IGR3, Q9I7N9
      Conserved Domains (1) summary
      cl00456
      Location:123 → 610
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    3. NM_135296.3 → NP_609140.2  uncharacterized protein Dmel_CG13796, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609140.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IGR3, Q9I7N9
      Conserved Domains (1) summary
      cl00456
      Location:123 → 610
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    4. NM_164766.3 → NP_723308.2  uncharacterized protein Dmel_CG13796, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723308.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IGR3, Q9I7N9
      Conserved Domains (1) summary
      cl00456
      Location:123 → 610
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IGR3 Q8IGR3
    Q9I7N9 Q9I7N9

    Gene LinkOut

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