Pburs Partner of Bursicon [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Pbursprovided by FlyBase
Official Full Name: Partner of Bursiconprovided by FlyBase
Primary source: FLYBASE:FBgn0264810
Locus tag: Dmel_CG15284
See related: AllianceGenome:FB:FBgn0264810
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: A; Bur beta; burs beta; Burs beta; burs-beta; bursbeta; Bursbeta; CG15284; Dmel\CG15284; pads-b; pburs; PBURS; pu; pup
Summary: Enables G protein-coupled receptor binding activity and protein heterodimerization activity. Contributes to neuropeptide hormone activity and neuropeptide receptor binding activity. Involved in G protein-coupled receptor signaling pathway; chitin-based cuticle sclerotization; and ecdysis, chitin-based cuticle. Located in extracellular region. Part of bursicon neuropeptide hormone complex. Is expressed in several structures, including abdominal neuromere; larval A1-A4 CCAP neuron; larval segment; and larval ventral nerve cord. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (14416729..14417331, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (14416729..14417331, complement)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables G protein-coupled receptor binding	IDA Inferred from Direct Assay more info	PubMed
enables G protein-coupled receptor binding	IEA Inferred from Electronic Annotation more info
contributes_to neuropeptide hormone activity	IC Inferred by Curator more info	PubMed
contributes_to neuropeptide hormone activity	IDA Inferred from Direct Assay more info	PubMed
enables neuropeptide hormone activity	IEA Inferred from Electronic Annotation more info
contributes_to neuropeptide receptor binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein heterodimerization activity	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in G protein-coupled receptor signaling pathway	IDA Inferred from Direct Assay more info	PubMed
involved_in chitin-based cuticle sclerotization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in ecdysis, chitin-based cuticle	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of bursicon neuropeptide hormone complex	IDA Inferred from Direct Assay more info	PubMed
part_of bursicon neuropeptide hormone complex	IEA Inferred from Electronic Annotation more info
part_of bursicon neuropeptide hormone complex	IPI Inferred from Physical Interaction more info	PubMed
is_active_in extracellular region	IBA Inferred from Biological aspect of Ancestor more info
located_in extracellular region	IDA Inferred from Direct Assay more info	PubMed

Names: CG15284-PA; Pburs-PA; bursicon; bursicon beta; bursicon beta subunit; bursicon beta-subunit; lethal group A; partner of burs; partner-of-bursicon; pupal