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    CG7849 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35537, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7849provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033060
    Locus tag
    Dmel_CG7849
    See related
    AllianceGenome:FB:FBgn0033060
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7849
    Summary
    Predicted to enable RNA binding activity and pseudouridine synthase activity. Predicted to be involved in RNA processing and pseudouridine synthesis. Orthologous to human TRUB2 (TruB pseudouridine synthase family member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7849 in Genome Data Viewer
    Location:
    42A9-42A9; 2-55 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (6076910..6078088)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (1964415..1965593)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44131 Neighboring gene lethal (2) k09848 Neighboring gene SET and MYND domain containing, arthropod-specific, member 5 Neighboring gene Arsenic resistance protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptome-wide analysis of pseudouridylation in Drosophila melanogaster. Song W, et al. G3 (Bethesda), 2023 Mar 9. PMID 36534986, Free PMC Article
    2. Nucleotide modifications in messenger RNA and their role in development and disease. Dezi V, et al. Biochem Soc Trans, 2016 Oct 15. PMID 27911721
    3. H/ACA snRNP-dependent ribosome biogenesis regulates translation of polyglutamine proteins. Breznak SM, et al. Sci Adv, 2023 Jun 23. PMID 37343092, Free PMC Article
    4. Reagent and Data Resources for Investigation of RNA Binding Protein Functions in Drosophila melanogaster Cultured Cells. Mohr SE, et al. G3 (Bethesda), 2015 Jul 21. PMID 26199285, Free PMC Article
    5. Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes. Hosono C, et al. Nat Cell Biol, 2015 Dec. PMID 26551273

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pseudouridine synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pseudouridine synthase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in pseudouridine synthesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in pseudouridine synthesis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial matrix ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7849-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      6076910..6078088
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136357.2 → NP_610201.1  uncharacterized protein Dmel_CG7849 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610201.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q29QN4
      Related
      FBpp0085330
      Conserved Domains (1) summary
      cd02868
      Location:18 → 292
      PseudoU_synth_hTruB2_like; Pseudouridine synthase, humanTRUB2_like
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q29QN4 Q29QN4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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