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    eIF3f2 eukaryotic translation initiation factor 3 subunit f2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35547, updated on 9-Dec-2024

    Summary

    Official Symbol
    eIF3f2provided by FlyBase
    Official Full Name
    eukaryotic translation initiation factor 3 subunit f2provided by FlyBase
    Primary source
    FLYBASE:FBgn0033069
    Locus tag
    Dmel_CG8335
    See related
    AllianceGenome:FB:FBgn0033069
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG8335; Dmel\CG8335; eIF3-S5; eIF3f
    Summary
    Predicted to enable metal-dependent deubiquitinase activity and translation initiation factor binding activity. Predicted to contribute to translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be part of eukaryotic translation initiation factor 3 complex, eIF3m. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 67. Orthologous to human EIF3F (eukaryotic translation initiation factor 3 subunit F). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See eIF3f2 in Genome Data Viewer
    Location:
    42A13-42A13; 2-55 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (6200853..6201956)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (2088358..2089461)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Patched-related Neighboring gene transfer RNA:Asparagine-GTT 1-8 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables metal-dependent deubiquitinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables metallopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to translation initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables translation initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables translation initiation factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables translation initiation factor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables translation initiation factor binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in translational initiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in translational initiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in translational initiation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of eukaryotic translation initiation factor 3 complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of eukaryotic translation initiation factor 3 complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    part_of eukaryotic translation initiation factor 3 complex, eIF3m IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    eukaryotic translation initiation factor 3 subunit f2
    Names
    CG8335-PA
    eIF3f2-PA
    NP_610210.2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      6200853..6201956
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136366.3NP_610210.2  eukaryotic translation initiation factor 3 subunit f2 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610210.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A1Z6K7
      UniProtKB/TrEMBL
      C6SUU7, H1UU98
      Related
      FBpp0085334
      Conserved Domains (1) summary
      cd08064
      Location:12280
      MPN_eIF3f; Mpr1p, Pad1p N-terminal (MPN) domains without catalytic isopeptidase activity, found in eIF3f