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    CG30046 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36334, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG30046provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0050046
    Locus tag
    Dmel_CG30046
    See related
    AllianceGenome:FB:FBgn0050046
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG17740; CT39323; Dmel\CG30046
    Summary
    Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in cell adhesion. Predicted to be located in basement membrane. Predicted to be active in extracellular matrix. Orthologous to human SPON1 (spondin 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG30046 in Genome Data Viewer
    Location:
    48F7-48F7; 2-66 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (12314117..12317573)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (8201622..8205078)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44316 Neighboring gene mitochondrial translation initiation factor 3 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Variation in the response to exercise stimulation in Drosophila: marathon runner versus sprinter genotypes. Riddle NC. J Exp Biol, 2020 Sep 21. PMID 32737212
    2. Gene expression profiling of brakeless mutant Drosophila embryos. Crona F, et al. Data Brief, 2015 Dec. PMID 26509186, Free PMC Article
    3. Flying toward a plastic-free world: Can Drosophila serve as a model organism to develop new strategies of plastic waste management? Pignataro E, et al. Sci Total Environ, 2024 Mar 1. PMID 38199375
    4. Transcriptomic analysis of inbreeding depression in cold-sensitive Drosophila melanogaster shows upregulation of the immune response. Vermeulen CJ, et al. J Evol Biol, 2013 Sep. PMID 23944235
    5. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in basement membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG30046-PB
    CG30046-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      12314117..12317573
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299412.1 → NP_001286341.1  uncharacterized protein Dmel_CG30046, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286341.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z8W6
      Conserved Domains (3) summary
      smart00209
      Location:510 → 561
      TSP1; Thrombospondin type 1 repeats
      cd08544
      Location:28 → 167
      Reeler; Reeler, the N-terminal domain of reelin, F-spondin, and a variety of other proteins
      pfam06468
      Location:194 → 382
      Spond_N; Spondin_N

    2. NM_165878.2 → NP_725129.1  uncharacterized protein Dmel_CG30046, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725129.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z8W6
      Related
      FBpp0087008
      Conserved Domains (3) summary
      smart00209
      Location:510 → 561
      TSP1; Thrombospondin type 1 repeats
      cd08544
      Location:28 → 167
      Reeler; Reeler, the N-terminal domain of reelin, F-spondin, and a variety of other proteins
      pfam06468
      Location:194 → 382
      Spond_N; Spondin_N
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1Z8W6 A1Z8W6
    Q8T988 Q8T988

    Gene LinkOut

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