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    CG42663 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36403, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG42663provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0261545
    Locus tag
    Dmel_CG42663
    See related
    AllianceGenome:FB:FBgn0261545
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:SD15892; CG12488; CG13486; CG18356; Dmel\CG42663
    Old locus tag
    Dmel_CG12488; Dmel_CG18356
    Summary
    Involved in determination of adult lifespan. Is expressed in embryonic antennal sense organ and embryonic hindgut. Orthologous to human NCKAP5 (NCK associated protein 5) and NCKAP5L (NCK associated protein 5 like). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG42663 in Genome Data Viewer
    Location:
    49C1-49C2; 2-67 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (12705172..12751545)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (8592677..8639050)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Wake-up-call Neighboring gene Mos oncogene Neighboring gene Tafazzin Neighboring gene mitochondrial ribosomal protein L18 Neighboring gene oxen

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A length-dependent evolutionarily conserved pathway controls nuclear export of circular RNAs. Huang C, et al. Genes Dev, 2018 May 1. PMID 29773557, Free PMC Article
    2. Unlimited Genetic Switches for Cell-Type-Specific Manipulation. Garcia-Marques J, et al. Neuron, 2019 Oct 23. PMID 31395429
    3. Misexpression screen delineates novel genes controlling Drosophila lifespan. Paik D, et al. Mech Ageing Dev, 2012 May. PMID 22366109, Free PMC Article
    4. The mRNA transportome of the BicD/Egl transport machinery. Vazquez-Pianzola P, et al. RNA Biol, 2017 Jan 2. PMID 27801632, Free PMC Article
    5. The Output of Protein-Coding Genes Shifts to Circular RNAs When the Pre-mRNA Processing Machinery Is Limiting. Liang D, et al. Mol Cell, 2017 Dec 7. PMID 29174924, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: 12707571-12715878 mobile_element_type = transposon:roo{}815

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in determination of adult lifespan IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG42663-PB
    CG42663-PC
    CG42663-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      12705172..12751545
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001201986.2 → NP_001188915.1  uncharacterized protein Dmel_CG42663, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188915.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F0JAQ8
      Conserved Domains (1) summary
      cl23748
      Location:111 → 209
      DUF3585; Protein of unknown function (DUF3585)

    2. NM_001273996.2 → NP_001260925.1  uncharacterized protein Dmel_CG42663, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260925.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KFS6
      Conserved Domains (1) summary
      cl23748
      Location:111 → 209
      DUF3585; Protein of unknown function (DUF3585)

    3. NM_136972.4 → NP_610816.2  uncharacterized protein Dmel_CG42663, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610816.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z951, E8NHB9
      Conserved Domains (1) summary
      cl23748
      Location:88 → 186
      DUF3585; Protein of unknown function (DUF3585)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KFS6 A0A0B4KFS6
    A1Z951 A1Z951
    F0JAQ8 F0JAQ8
    Q8MRX6 Q8MRX6

    Gene LinkOut

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