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    CG30394 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37437, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG30394provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0050394
    Locus tag
    Dmel_CG30394
    See related
    AllianceGenome:FB:FBgn0050394
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0172774.187; anon-WO0172774.188; CG10500; CG15670; Dmel\CG30394
    Summary
    Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to be active in membrane. Is expressed in several structures, including anterior-posterior subdivision of organism; embryonic proventriculus; embryonic proventriculus inner layer; embryonic/larval garland cell; and gland. Orthologous to human SLC38A10 (solute carrier family 38 member 10). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG30394 in Genome Data Viewer
    Location:
    57D11-57D11; 2-94 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (21320040..21323320, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (17207545..17210825, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Ankyrin repeat-rich membrane spanning Neighboring gene Panoramix Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene domino

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Knockdown of SLC38 Transporter Ortholog - CG13743 Reveals a Metabolic Relevance in Drosophila. Aggarwal T, et al. Front Physiol, 2019. PMID 32038282, Free PMC Article
    2. dMyc-dependent upregulation of CD98 amino acid transporters is required for Drosophila brain tumor growth. Rebelo AR, et al. Cell Mol Life Sci, 2023 Jan 6. PMID 36609617, Free PMC Article
    3. Differential amino acid transporter expression in adult Drosophila melanogaster tissues. Wright Y, et al. MicroPubl Biol, 2024. PMID 38481556, Free PMC Article
    4. A post-ingestive amino acid sensor promotes food consumption in Drosophila. Yang Z, et al. Cell Res, 2018 Oct. PMID 30209352, Free PMC Article
    5. Glial solute carrier transporters in Drosophila and mice. Featherstone DE. Glia, 2011 Sep. PMID 21732427

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables L-amino acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables amino acid transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in amino acid transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in amino acid transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG30394-PA
    CG30394-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      21320040..21323320 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137734.4 → NP_611578.1  uncharacterized protein Dmel_CG30394, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611578.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SY25, Q9W2H7
      Related
      FBpp0071539
      Conserved Domains (4) summary
      COG0814
      Location:8 → 392
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      pfam16001
      Location:394 → 652
      DUF4775; Domain of unknown function (DUF4775)
      cl00456
      Location:8 → 390
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
      cl01868
      Location:561 → 660
      YukC; WXG100 protein secretion system (Wss), protein YukC

    2. NM_137735.3 → NP_611579.1  uncharacterized protein Dmel_CG30394, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611579.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SY25, Q9W2H7
      Related
      FBpp0071540
      Conserved Domains (4) summary
      COG0814
      Location:8 → 392
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      pfam16001
      Location:394 → 652
      DUF4775; Domain of unknown function (DUF4775)
      cl00456
      Location:8 → 390
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
      cl01868
      Location:561 → 660
      YukC; WXG100 protein secretion system (Wss), protein YukC
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MSA1 Q8MSA1
    Q8SY25 Q8SY25

    Gene LinkOut

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