U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG10477 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38679, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG10477provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035661
    Locus tag
    Dmel_CG10477
    See related
    AllianceGenome:FB:FBgn0035661
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0140519.232; Dmel\CG10477; SP51
    Summary
    Enables serine hydrolase activity. Predicted to be involved in innate immune response and proteolysis. Predicted to be active in extracellular space. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG10477 in Genome Data Viewer
    Location:
    65A3-65A3; 3-16 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (6033199..6034611, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (6026299..6027711, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45440 Neighboring gene PVR adaptor protein Neighboring gene alpha Karyopherin-4 Neighboring gene long non-coding RNA:CR43952 Neighboring gene yippee interacting protein 7

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Buffering and proteolysis are induced by segmental monosomy in Drosophila melanogaster. Lundberg LE, et al. Nucleic Acids Res, 2012 Jul. PMID 22434883, Free PMC Article
    2. Genes encoding Drosophila melanogaster RNA polymerase II general transcription factors: diversity in TFIIA and TFIID components contributes to gene-specific transcriptional regulation. Aoyagi N, et al. J Cell Biol, 2000 Jul 24. PMID 10908585, Free PMC Article
    3. Damage sensing mediated by serine proteases Hayan and Persephone for Toll pathway activation in apoptosis-deficient flies. Nakano S, et al. PLoS Genet, 2023 Jun. PMID 37319131, Free PMC Article
    4. Use of mutagenesis, genetic mapping and next generation transcriptomics to investigate insecticide resistance mechanisms. Kalajdzic P, et al. PLoS One, 2012. PMID 22768270, Free PMC Article
    5. Two subunits specific to the PBAP chromatin remodeling complex have distinct and redundant functions during drosophila development. Carrera I, et al. Mol Cell Biol, 2008 Sep. PMID 18573871, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables endopeptidase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    enables serine hydrolase activity HDA PubMed 
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type endopeptidase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteolysis ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG10477-PA
    CG10477-PB
    NF-YB-like
    NP_001303385.1
    NP_648010.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      6033199..6034611 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139753.2 → NP_648010.1  uncharacterized protein Dmel_CG10477, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648010.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      L7S4W3, Q9VRS3
      Related
      FBpp0076776
      Conserved Domains (2) summary
      smart00020
      Location:39 → 264
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:40 → 267
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

    2. NM_001316456.1 → NP_001303385.1  uncharacterized protein Dmel_CG10477, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      L7S4W3, Q9VRS3
      Conserved Domains (2) summary
      smart00020
      Location:39 → 264
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:40 → 267
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VRS3 Q9VRS3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools