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    Elo68beta Elongase 68beta [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39245, updated on 9-Dec-2024

    Summary

    Official Symbol
    Elo68betaprovided by FlyBase
    Official Full Name
    Elongase 68betaprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036128
    Locus tag
    Dmel_CG11801
    See related
    AllianceGenome:FB:FBgn0036128
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG11801; Dmel\CG11801; elo68beta
    Summary
    Predicted to enable fatty acid elongase activity. Predicted to be involved in fatty acid biosynthetic process and sphingolipid biosynthetic process. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in corneal dystrophy and spinocerebellar ataxia type 34. Orthologous to human ELOVL4 (ELOVL fatty acid elongase 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See Elo68beta in Genome Data Viewer
    Location:
    68A6-68A6; 3-34 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (11100675..11101698, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (11093775..11094798, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Inverted repeat binding protein 18 kDa Neighboring gene beta-Amyloid precursor protein binding protein 1 Neighboring gene Elongase 68alpha Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables fatty acid elongase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables fatty acid elongase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables fatty acid elongase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in fatty acid elongation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in fatty acid elongation, monounsaturated fatty acid IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in fatty acid elongation, polyunsaturated fatty acid IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in fatty acid elongation, saturated fatty acid IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in sphingolipid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in very long-chain fatty acid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    elongase 68beta
    Names
    CG11801-PB
    Elo68beta-PB
    NP_001097580.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      11100675..11101698 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001104110.4NP_001097580.1  elongase 68beta [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097580.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JNR0
      Conserved Domains (1) summary
      pfam01151
      Location:48267
      ELO; GNS1/SUR4 family