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    dsx-c73A doublesex cognate 73A [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39831, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dsx-c73Aprovided by FlyBase
    Official Full Name
    doublesex cognate 73Aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0261799
    Locus tag
    Dmel_CG32159
    See related
    AllianceGenome:FB:FBgn0261799
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13034; CG32159; CG4541; Dmel\CG32159; dsc73; DSC73; dsx-c73; dsx-c73a; dsxc73A; l(3)j10E8
    Summary
    Predicted to be a structural constituent of nuclear pore. Involved in chitin-based cuticle development. Located in chitin-based extracellular matrix. Is expressed in several structures, including Kolbchen; adult brain cell body rind; cuticular specialization; epithelium; and gut section. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See dsx-c73A in Genome Data Viewer
    Location:
    72F1-73A1; 3-44 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (16422795..16451958, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (16415895..16445058, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Serine incorporator Neighboring gene Glutamyl-tRNA synthetase, mitochondrial Neighboring gene uncharacterized protein Neighboring gene Tyrosyl-tRNA synthetase Neighboring gene argos Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression of the Drosophila secreted cuticle protein 73 (dsc73) requires Shavenbaby. Andrew DJ, et al. Dev Dyn, 2008 Apr. PMID 18351665, Free PMC Article
    2. Identification of novel direct targets of Drosophila Sine oculis and Eyes absent by integration of genome-wide data sets. Jin M, et al. Dev Biol, 2016 Jul 1. PMID 27178668, Free PMC Article
    3. The Drosophila dCREB-A gene is required for dorsal/ventral patterning of the larval cuticle. Andrew DJ, et al. Development, 1997 Jan. PMID 9006079
    4. The transcription factor Grainy head and the steroid hormone ecdysone cooperate during differentiation of the skin of Drosophila melanogaster. Gangishetti U, et al. Insect Mol Biol, 2012 Jun. PMID 22458773
    5. The genetic architecture of larval aggregation behavior in Drosophila. McKinney RM, et al. J Neurogenet, 2021 Sep. PMID 33629904

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of chitin-based cuticle IC
    Inferred by Curator
    more info
    		 PubMed 
    enables structural constituent of nuclear pore IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in chitin-based cuticle development IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in mRNA export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of mitotic spindle assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in chitin-based extracellular matrix IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of nuclear pore IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in perivitelline space HDA PubMed 

    General protein information

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    Preferred Names
    doublesex cognate 73A
    Names
    CG32159-PB
    drosophila secreted cuticle protein 73
    dsx-c73A-PB
    lethal (3) j10E8

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      16422795..16451958 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168667.3 → NP_730169.1  doublesex cognate 73A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730169.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SZ17, Q9VV62
      Related
      FBpp0075167
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VV62 Q9VV62

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