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    Dso1 Daisho1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 50126, updated on 17-Dec-2024

    Summary

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    Official Symbol
    Dso1provided by FlyBase
    Official Full Name
    Daisho1provided by FlyBase
    Primary source
    FLYBASE:FBgn0040653
    Locus tag
    Dmel_CG15231
    See related
    AllianceGenome:FB:FBgn0040653
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RH25931; CG15231; DIM 4; DIM-4; DIM4; Dmel\CG15231; dso1; IM4
    Summary
    Involved in antifungal humoral response. Located in extracellular space. Is expressed in embryonic/larval hemolymph and larval central nervous system. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Dso1 in Genome Data Viewer
    Location:
    57B3-57B3; 2-92 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (20868496..20869321, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16756001..16756826, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Carbonic anhydrase 14 Neighboring gene Daisho2 Neighboring gene Inositol phosphate kinase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Daisho Peptides Mediate Drosophila Defense Against a Subset of Filamentous Fungi. Cohen LB, et al. Front Immunol, 2020. PMID 32038657, Free PMC Article
    2. An unusual Toll/MyD88-mediated Drosophila host defence against Talaromyces marneffei. Wang X, et al. Fly (Austin), 2024 Dec. PMID 39239739, Free PMC Article
    3. A Toll pathway effector protects Drosophila specifically from distinct toxins secreted by a fungus or a bacterium. Huang J, et al. Proc Natl Acad Sci U S A, 2023 Mar 21. PMID 36917667, Free PMC Article
    4. Hazardous effects of octopamine receptor agonists on altering metabolism-related genes and behavior of Drosophila melanogaster. Ahmed MAI, et al. Chemosphere, 2020 Aug. PMID 32283422, Free PMC Article
    5. Exploring the multilevel hazards of thiamethoxam using Drosophila melanogaster. Li X, et al. J Hazard Mater, 2020 Feb 15. PMID 31630861

    See all (78) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in antifungal humoral response IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in defense response IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in defense response NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in humoral immune response IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to bacterium HEP PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in extracellular space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Daisho1
    Names
    CG15231-PA
    CG15231-PB
    Dso1-PA
    Dso1-PB
    daisho1
    drosophila immune-induced molecule 4
    immune induced molecule 4
    immune induced peptide 4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      20868496..20869321 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299719.1 → NP_001286648.1  Daisho1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286648.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A0B4LG54, P82705, Q9W2Q9

    2. NM_144038.3 → NP_652295.1  Daisho1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_652295.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A0B4LG54, P82705, Q9W2Q9
      Related
      FBpp0071487
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P82705.2 P82705

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