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    CG18675 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 50169, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG18675provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0040696
    Locus tag
    Dmel_CG18675
    See related
    AllianceGenome:FB:FBgn0040696
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG18675
    Summary
    Predicted to be involved in regulation of cilium movement. Is expressed in several structures, including embryonic head sensory system; embryonic labial sensory complex; embryonic maxillary sensory complex; sensory nervous system primordium; and ventral sensory complex anlage. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 26. Orthologous to human CFAP298 (cilia and flagella associated protein 298). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG18675 in Genome Data Viewer
    Location:
    64A9-64A10; 3-10 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (4173884..4192968)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (4173884..4192968)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44529 Neighboring gene Endoplasmic reticulum oxidoreductin-1-like Neighboring gene tipE homolog 4 Neighboring gene tipE homolog 2 Neighboring gene Vacuolar H[+] ATPase M9.7 subunit c Neighboring gene tipE homolog 3 Neighboring gene temperature-induced paralytic E Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Cuticular protein 64Aa

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A remarkably stable TipE gene cluster: evolution of insect Para sodium channel auxiliary subunits. Li J, et al. BMC Evol Biol, 2011 Nov 18. PMID 22098672, Free PMC Article
    2. Decoding cilia function: defining specialized genes required for compartmentalized cilia biogenesis. Avidor-Reiss T, et al. Cell, 2004 May 14. PMID 15137945
    3. Survey of the Ciliary Motility Machinery of Drosophila Sperm and Ciliated Mechanosensory Neurons Reveals Unexpected Cell-Type Specific Variations: A Model for Motile Ciliopathies. Zur Lage P, et al. Front Genet, 2019. PMID 30774648, Free PMC Article
    4. Identification of neural outgrowth genes using genome-wide RNAi. Sepp KJ, et al. PLoS Genet, 2008 Jul 4. PMID 18604272, Free PMC Article
    5. Global analysis of patterns of gene expression during Drosophila embryogenesis. Tomancak P, et al. Genome Biol, 2007. PMID 17645804, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of cilium movement IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG18675-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      4173884..4192968
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_144077.3 → NP_652334.2  uncharacterized protein Dmel_CG18675 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_652334.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8T478, Q9VZH1
      Related
      FBpp0073074
      Conserved Domains (1) summary
      pfam11069
      Location:189 → 285
      DUF2870; Protein of unknown function (DUF2870)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VZH1.2 Q9VZH1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
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