U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Atg10 Autophagy-related 10 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 50253, updated on 9-Dec-2024

    Summary

    Official Symbol
    Atg10provided by FlyBase
    Official Full Name
    Autophagy-related 10provided by FlyBase
    Primary source
    FLYBASE:FBgn0040780
    Locus tag
    Dmel_CG12821
    See related
    AllianceGenome:FB:FBgn0040780
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    atg10; ATG10; CG12821; Dmel\CG12821
    Summary
    Predicted to enable Atg12 conjugating enzyme activity. Predicted to be involved in macroautophagy and protein modification process. Predicted to be active in phagophore assembly site. Orthologous to human ATG10 (autophagy related 10). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Atg10 in Genome Data Viewer
    Location:
    43E18-43E18; 2-57 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (7832171..7835518)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (3719676..3723023)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Proteasome alpha1 subunit Neighboring gene Proteasome alpha1 subunit-related Neighboring gene uncharacterized protein Neighboring gene photorepair Neighboring gene uncharacterized protein Neighboring gene Diacyl glycerol kinase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Cullin 1 Neighboring gene Odorant receptor 43b

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables Atg12 conjugating enzyme activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables Atg12 transferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables ubiquitin-like protein transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ubiquitin-like protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in autophagosome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in glycophagy IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in macroautophagy ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in nucleophagy IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein modification process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in phagophore assembly site IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Autophagy-related 10
    Names
    Atg10-PB
    Atg10-PD
    Autophagy-specific gene 10
    CG12821-PB
    CG12821-PD

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      7832171..7835518
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001103746.3NP_001097216.2  Autophagy-related 10, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097216.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q3ZAP6, Q4V6A8
      Conserved Domains (1) summary
      pfam03987
      Location:66130
      Autophagy_act_C; Autophagocytosis associated protein, active-site domain
    2. NM_001103745.3NP_001097215.1  Autophagy-related 10, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097215.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q3ZAP6, Q4V6A8
      Conserved Domains (1) summary
      pfam03987
      Location:66130
      Autophagy_act_C; Autophagocytosis associated protein, active-site domain