Fam92 Fam92 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Fam92provided by FlyBase
Official Full Name: Fam92provided by FlyBase
Primary source: FLYBASE:FBgn0032428
Locus tag: Dmel_CG6405
See related: AllianceGenome:FB:FBgn0032428
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG6405; Dmel\CG6405; fam92; FAM92
Summary: Predicted to be involved in cilium assembly and negative regulation of protein secretion. Located in ciliary basal body; ciliary transition zone; and dendrite. Orthologous to human CIBAR1 (CBY1 interacting BAR domain containing 1) and CIBAR2 (CBY1 interacting BAR domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (12424904..12426440)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (12424904..12426440)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Dzip1 and Fam92 form a ciliary transition zone complex with cell type specific roles in Drosophila.
Title: Dzip1 and Fam92 form a ciliary transition zone complex with cell type specific roles in Drosophila.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Process	Evidence Code	Pubs
involved_in cilium assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in cilium assembly	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of protein secretion	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in ciliary basal body	IBA Inferred from Biological aspect of Ancestor more info
located_in ciliary basal body	IDA Inferred from Direct Assay more info	PubMed
is_active_in ciliary transition zone	IBA Inferred from Biological aspect of Ancestor more info
located_in ciliary transition zone	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
located_in dendrite	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info