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    Obp69a Odorant-binding protein 69a [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39411, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Obp69aprovided by FlyBase
    Official Full Name
    Odorant-binding protein 69aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0011279
    Locus tag
    Dmel_CG10436
    See related
    AllianceGenome:FB:FBgn0011279
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    69a; CG10436; DmelObp69a; Dmel\CG10436; OBP69a; PB-PRP1; PBP1; pbprp-1; PBPRP-1; pbprp1; Pbprp1
    Summary
    Predicted to enable phenylalkylamine binding activity and pheromone binding activity. Involved in several processes, including courtship behavior; olfactory behavior; and sensory perception of smell. Located in extracellular region. Is expressed in antenna; antennal segment 3 sense organ; antennal sense organ; third segment of antenna; and trichoid sensillum of antennal segment 3. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Obp69a in Genome Data Viewer
    Location:
    69B4-69B4; 3-38 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (12396171..12396957)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (12389271..12390057)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Corazonin receptor Neighboring gene sodium chloride cotransporter 69 Neighboring gene long non-coding RNA:CR45824 Neighboring gene uncharacterized protein Neighboring gene SET and MYND domain containing, class 4, member 2 Neighboring gene Short Calcium-binding Mitochondrial Carrier

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Odorant binding protein 69a connects social interaction to modulation of social responsiveness in Drosophila. Bentzur A, et al. PLoS Genet, 2018 Apr. PMID 29630598, Free PMC Article
    2. LUSH odorant-binding protein mediates chemosensory responses to alcohols in Drosophila melanogaster. Kim MS, et al. Genetics, 1998 Oct. PMID 9755202, Free PMC Article
    3. Members of a family of Drosophila putative odorant-binding proteins are expressed in different subsets of olfactory hairs. Pikielny CW, et al. Neuron, 1994 Jan. PMID 7545907
    4. Expression patterns of two putative odorant-binding proteins in the olfactory organs of Drosophila melanogaster have different implications for their functions. Park SK, et al. Cell Tissue Res, 2000 Apr. PMID 10805087
    5. The genetics of olfaction. Griff IC, et al. Curr Opin Genet Dev, 1995 Oct. PMID 8664555

    See all (54) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables odorant binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables odorant binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables phenylalkylamine binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables pheromone binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in courtship behavior IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in olfactory behavior IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to pheromone IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sensory perception of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in sensory perception of smell IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sensory perception of smell IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Odorant-binding protein 69a
    Names
    CG10436-PA
    Obp69a-PA
    Pbprp1
    Pheromone-binding protein-related protein 1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      12396171..12396957
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079315.2 → NP_524039.2  Odorant-binding protein 69a [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524039.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P54191, Q9VTX0
      Related
      FBpp0075687, FBtr0075955
      Conserved Domains (1) summary
      pfam01395
      Location:26 → 133
      PBP_GOBP; PBP/GOBP family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P54191.2 P54191

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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