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    CG14803 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31142, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG14803provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0023513
    Locus tag
    Dmel_CG14803
    See related
    AllianceGenome:FB:FBgn0023513
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG14803; EG:63B12.9
    Summary
    Predicted to be involved in double-strand break repair via homologous recombination and replication fork processing. Predicted to be active in nuclear replication fork. Is expressed in organism and spermatozoon. Orthologous to human MMS22L (MMS22 like, DNA repair protein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG14803 in Genome Data Viewer
    Location:
    2B13-2B13; 1-0.2 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (1868870..1872408)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (1762903..1766441)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Germ cell nuclear acidic peptidase Neighboring gene Mediator complex subunit 18 Neighboring gene Peroxin 5 Neighboring gene Phosphoglycerate mutase 5 Neighboring gene Vacuolar protein sorting 26 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic effects in Drosophila on the potency of diverse general anesthetics: a distinctive pattern of altered sensitivity. Campbell JL, et al. J Neurogenet, 2009. PMID 19863272, Free PMC Article
    2. The Drosophila MSL complex activates the transcription of target genes. Straub T, et al. Genes Dev, 2005 Oct 1. PMID 16204179, Free PMC Article
    3. Identification of genes expressed during Drosophila melanogaster gastrulation by using subtractive hybridization. González-Agüero M, et al. Gene, 2005 Jan 31. PMID 15716118
    4. From first base: the sequence of the tip of the X chromosome of Drosophila melanogaster, a comparison of two sequencing strategies. Benos PV, et al. Genome Res, 2001 May. PMID 11337470, Free PMC Article
    5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in double-strand break repair via homologous recombination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in double-strand break repair via homologous recombination IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in double-strand break repair via homologous recombination ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in replication fork processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in replication fork processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in replication fork processing ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nuclear replication fork IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nuclear replication fork ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG14803-PA
    CG14803-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      1868870..1872408
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130594.2 → NP_569950.1  uncharacterized protein Dmel_CG14803, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_569950.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D0Z773, O46089, Q9W553
      Related
      FBpp0070297
      Conserved Domains (2) summary
      pfam14910
      Location:195 → 559
      MMS22L_N; S-phase genomic integrity recombination mediator, N-terminal
      pfam14911
      Location:733 → 1099
      MMS22L_C; S-phase genomic integrity recombination mediator, C-terminal

    2. NM_001297865.1 → NP_001284794.1  uncharacterized protein Dmel_CG14803, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284794.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X2JA69
      Conserved Domains (2) summary
      pfam14910
      Location:190 → 554
      MMS22L_N; S-phase genomic integrity recombination mediator, N-terminal
      pfam14911
      Location:728 → 1094
      MMS22L_C; S-phase genomic integrity recombination mediator, C-terminal
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O46089.2 O46089
    X2JA69 X2JA69

    Gene LinkOut

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