U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    dao down and out [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34891, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    daoprovided by FlyBase
    Official Full Name
    down and outprovided by FlyBase
    Primary source
    FLYBASE:FBgn0028862
    Locus tag
    Dmel_CG15267
    See related
    AllianceGenome:FB:FBgn0028862
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0140519.126; BG:DS07295.2; CG15267; Dmel\CG15267
    Summary
    Located in plasma membrane. Is expressed in adult head; embryonic brain; and larval ventral nerve cord. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See dao in Genome Data Viewer
    Location:
    35C5-35C5; 2-51 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (15248879..15254715)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (15248879..15254715)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Zinc transporter 35C Neighboring gene DNA polymerase delta subunit 3 Neighboring gene Uxt prefoldin-like subunit Neighboring gene yuri gagarin

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Loss of Pol32 in Drosophila melanogaster causes chromosome instability and suppresses variegation. Tritto P, et al. PLoS One, 2015. PMID 25826374, Free PMC Article
    2. A Drosophila behavioral mutant, down and out (dao), is defective in an essential regulator of Erg potassium channels. Fergestad T, et al. Proc Natl Acad Sci U S A, 2010 Mar 23. PMID 20212103, Free PMC Article
    3. Retinoblastoma family 2 is required in vivo for the tissue-specific repression of dE2F2 target genes. Stevaux O, et al. Cell Cycle, 2005 Sep. PMID 16082225
    4. An exploration of the sequence of a 2.9-Mb region of the genome of Drosophila melanogaster: the Adh region. Ashburner M, et al. Genetics, 1999 Sep. PMID 10471707, Free PMC Article
    5. Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach. Pazos Obregón F, et al. BMC Genomics, 2015 Sep 15. PMID 26370122, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    down and out
    Names
    CG15267-PA
    CG15267-PB
    CG15267-PC
    dao-PA
    dao-PB
    dao-PC

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      15248879..15254715
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273533.1 → NP_001260462.1  down and out, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260462.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B5X511, Q4V5D2, Q9V3J9
      Conserved Domains (3) summary
      sd00006
      Location:200 → 235
      TPR; TPR repeat [structural motif]
      pfam01753
      Location:355 → 395
      zf-MYND; MYND finger
      pfam13414
      Location:165 → 235
      TPR_11; TPR repeat

    2. NM_135898.4 → NP_609742.1  down and out, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609742.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B5X511, Q4V5D2, Q9V3J9
      Related
      FBpp0080267
      Conserved Domains (3) summary
      sd00006
      Location:200 → 235
      TPR; TPR repeat [structural motif]
      pfam01753
      Location:355 → 395
      zf-MYND; MYND finger
      pfam13414
      Location:165 → 235
      TPR_11; TPR repeat

    3. NM_001273534.1 → NP_001260463.1  down and out, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260463.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B5X511, M9PBB6, Q4V5D2
      Conserved Domains (3) summary
      sd00006
      Location:200 → 235
      TPR; TPR repeat [structural motif]
      pfam01753
      Location:355 → 395
      zf-MYND; MYND finger
      pfam13414
      Location:165 → 235
      TPR_11; TPR repeat
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PBB6 M9PBB6
    Q9V3J9 Q9V3J9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools