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    CG14535 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34073, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG14535provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031955
    Locus tag
    Dmel_CG14535
    See related
    AllianceGenome:FB:FBgn0031955
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG14535; DmKIF26; KIF26; KIF26A/B
    Summary
    Predicted to enable microtubule binding activity. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations. Orthologous to human KIF26A (kinesin family member 26A) and KIF26B (kinesin family member 26B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG14535 in Genome Data Viewer
    Location:
    28D2-28D2; 2-29 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (7844905..7855475, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (7844905..7855475, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene lectin-28C Neighboring gene TweedleE Neighboring gene Proctolin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evidence for involvement of the alcohol consumption WDPCP gene in lipid metabolism, and liver cirrhosis. O'Farrell F, et al. Sci Rep, 2023 Nov 23. PMID 37996473, Free PMC Article
    2. Analysis of the kinesin superfamily: insights into structure and function. Miki H, et al. Trends Cell Biol, 2005 Sep. PMID 16084724
    3. The kinesin motor Klp98A mediates apical to basal Wg transport. Witte L, et al. Development, 2020 Aug 14. PMID 32665246, Free PMC Article
    4. Identification of neural outgrowth genes using genome-wide RNAi. Sepp KJ, et al. PLoS Genet, 2008 Jul 4. PMID 18604272, Free PMC Article
    5. Reconstructing the phylogeny of 21 completely sequenced arthropod species based on their motor proteins. Odronitz F, et al. BMC Genomics, 2009 Apr 21. PMID 19383156, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    NOT enables ATP hydrolysis activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables microtubule binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    NOT enables microtubule motor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    NOT involved_in microtubule-based movement ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG14535-PA
    CG14535-PB
    Kinesin11
    kinesin superfamily protein 26

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      7844905..7855475 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298797.1 → NP_001285726.1  uncharacterized protein Dmel_CG14535, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285726.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VLW2
      UniProtKB/TrEMBL
      X2J924
      Conserved Domains (1) summary
      cl22853
      Location:44 → 394
      Motor_domain; Myosin and Kinesin motor domain

    2. NM_135312.2 → NP_609156.1  uncharacterized protein Dmel_CG14535, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609156.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VLW2
      UniProtKB/TrEMBL
      X2J924
      Related
      FBpp0079186
      Conserved Domains (1) summary
      cl22853
      Location:44 → 394
      Motor_domain; Myosin and Kinesin motor domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VLW2.2 Q9VLW2
    X2J924 X2J924

    Gene LinkOut

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