U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    RpL23A Ribosomal protein L23A [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38208, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    RpL23Aprovided by FlyBase
    Official Full Name
    Ribosomal protein L23Aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0026372
    Locus tag
    Dmel_CG7977
    See related
    AllianceGenome:FB:FBgn0026372
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    153215_at; anon-EST:fe2D1; anon-EST:Liang-1.4; CG7977; clone 1.4; Dmel\CG7977; eRpL23a; L23; L23a; L23A; PBP-3; Rp L23A; rpl23a; RpL23a; RPL23a; rpL25; RpL25
    Summary
    A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Located in cytosolic ribosome. Is expressed in adult head; adult heart; and organism. Orthologous to human RPL23A (ribosomal protein L23a). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See RpL23A in Genome Data Viewer
    Location:
    62A10-62A10; 3-0.5 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (1666288..1668654, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (1667192..1668654, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Vesicle trafficking 1 Neighboring gene uncharacterized protein Neighboring gene Serine-arginine repetitive matrix 2/3/4 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene snoRNA:Orphan C/D box 15 Neighboring gene uncharacterized protein Neighboring gene U snoRNA host gene 7 Neighboring gene RabX5 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Functional conservation between structurally diverse ribosomal proteins from Drosophila melanogaster and Saccharomyces cerevisiae: fly L23a can substitute for yeast L25 in ribosome assembly and function. Ross CL, et al. Nucleic Acids Res, 2007. PMID 17584789, Free PMC Article
    2. Poly(ADP-ribose) polymerase interacts with novel Drosophila ribosomal proteins, L22 and l23a, with unique histone-like amino-terminal extensions. Koyama Y, et al. Gene, 1999 Jan 21. PMID 9931508
    3. Genomic organization of the segment polarity gene pan in Drosophila melanogaster. Dooijes D, et al. Mol Gen Genet, 1998 Apr. PMID 9613571
    4. Specialized eRpL22 paralogue-specific ribosomes regulate specific mRNA translation in spermatogenesis in Drosophila melanogaster. Mageeney CM, et al. Mol Biol Cell, 2019 Aug 1. PMID 31188709, Free PMC Article
    5. A Simple Cross-Linking/Mass Spectrometry Workflow for Studying System-wide Protein Interactions. Götze M, et al. Anal Chem, 2019 Aug 6. PMID 31283178

    See all (72) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. In order to test the function of D. melanogaster L23a and to gain insight into the interchangeability of L23 ribosomal components, D. melanogaster L23a was substituted for yeast L25 in ribosome assembly and function.
      Title: Functional conservation between structurally diverse ribosomal proteins from Drosophila melanogaster and Saccharomyces cerevisiae: fly L23a can substitute for yeast L25 in ribosome assembly and function.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables rRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome HDA PubMed 
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in cytoplasmic translation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in cytosolic ribosome HDA PubMed 
    located_in cytosolic ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    ribosomal protein L23A
    Names
    CG7977-PA
    CG7977-PB
    PARP-binding protein-3
    RpL23A-PA
    RpL23A-PB
    anon-fast-evolving-2D1
    ribosomal protein L23a
    ribosomal protein L25

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      1666288..1668654 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001370049.1 → NP_001356972.1  ribosomal protein L23A, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0ZHI2, Q9W0A8
      Conserved Domains (1) summary
      PTZ00191
      Location:132 → 277
      PTZ00191; 60S ribosomal protein L23a; Provisional

    2. NM_079162.4 → NP_523886.1  ribosomal protein L23A, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523886.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0ZHI2, Q9W0A8
      Related
      FBpp0072687
      Conserved Domains (1) summary
      PTZ00191
      Location:132 → 277
      PTZ00191; 60S ribosomal protein L23a; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O97118 O97118
    Q0ZHI2 Q0ZHI2
    Q5BHZ4 Q5BHZ4
    Q8SX05 Q8SX05
    Q9W0A8 Q9W0A8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous