mats mob as tumor suppressor [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: matsprovided by FlyBase
Official Full Name: mob as tumor suppressorprovided by FlyBase
Primary source: FLYBASE:FBgn0038965
Locus tag: Dmel_CG13852
See related: AllianceGenome:FB:FBgn0038965
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-WO0118547.303; CG13852; Dmel\CG13852; dmob1; Dmob1; DMob1; Mats; MATS; Mob; Mob1; Mob1A/B
Summary: Enables protein kinase activator activity and protein kinase binding activity. Involved in several processes, including follicle cell of egg chamber development; hippo signaling; and negative regulation of cell population proliferation. Located in several cellular components, including centrosome; cytosol; and nucleus. Is expressed in embryonic/larval anterior midgut; eye disc; leg disc; organism; and wing disc. Orthologous to several human genes including MOB1A (MOB kinase activator 1A). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (22421161..22423302)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (18246883..18249024)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein kinase activator activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein kinase activator activity	IDA Inferred from Direct Assay more info	PubMed
enables protein kinase activator activity	IGI Inferred from Genetic Interaction more info	PubMed
enables protein kinase binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in apoptotic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in chromosome segregation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in follicle cell of egg chamber development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in hippo signaling	IBA Inferred from Biological aspect of Ancestor more info
involved_in hippo signaling	IGI Inferred from Genetic Interaction more info	PubMed
involved_in hippo signaling	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of cell population proliferation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in signal transduction	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in centrosome	IDA Inferred from Direct Assay more info	PubMed
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed

Names: CG13852-PA; CG13852-PB; CG13852-PC; Mob as tumor suppresso; Mob as tumor suppressor; Mob-as-tumor-supressor; mats; mats-PA; mats-PB; mats-PC

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain