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    nimT 2-nitroimidazole exporter [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946309, updated on 17-Dec-2024

    Summary

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    Official Symbol
    nimT
    Official Full Name
    2-nitroimidazole exporter
    Primary source
    ECOCYC:G6977
    Locus tag
    b1791
    See related
    ASAP:ABE-0005962
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1789; yeaN
    Summary
    Major Facilitator Superfamily (MFS). [More information is available at EcoGene: EG13500]. The YeaN protein is an uncharacterised member of the major facilitator superfamily (MFS) of transporters . [More information is available at EcoCyc: G6977].
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    Genomic context

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    Sequence:
    NC_000913.3 (1875673..1876854)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene protein YoaI Neighboring gene DUF441 domain-containing inner membrane protein YeaL Neighboring gene DNA-binding transcriptional repressor NimR Neighboring gene DUF488 domain-containing protein YeaO Neighboring gene DUF333 domain-containing lipoprotein YoaF

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of pathogen-specific and conserved genes expressed in vivo by an avian pathogenic Escherichia coli strain. Dozois CM, et al. Proc Natl Acad Sci U S A, 2003 Jan 7. PMID 12506201, Free PMC Article
    2. Role of transcription factor NimR (YeaM) in sensitivity control of Escherichia coli to 2-nitroimidazole. Ogasawara H, et al. FEMS Microbiol Lett, 2015 Jan. PMID 25790494
    3. Microbial drug efflux proteins of the major facilitator superfamily. Saidijam M, et al. Curr Drug Targets, 2006 Jul. PMID 16842212
    4. The major facilitator superfamily. Saier MH Jr, et al. J Mol Microbiol Biotechnol, 1999 Nov. PMID 10943556
    5. A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport. Marger MD, et al. Trends Biochem Sci, 1993 Jan. PMID 8438231

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transmembrane transporter activity RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in response to antibiotic IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to antibiotic IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within transmembrane transport RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    2-nitroimidazole exporter

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1875673..1876854
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416305.1 2-nitroimidazole exporter [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416305.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8H9T0N9, A0A8T5Y8J3
      Conserved Domains (1) summary
      cd17409
      Location:16 → 388
      MFS_NIMT_like; 2-nitroimidazole transporter and similar proteins of the Major Facilitator Superfamily of transporters
    Nucleotide Protein
    Heading Accession and Version

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