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    codB cytosine transporter [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 944994, updated on 3-Dec-2024

    Summary

    Official Symbol
    codB
    Official Full Name
    cytosine transporter
    Primary source
    ECOCYC:EG11327
    Locus tag
    b0336
    See related
    ASAP:ABE-0001159
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0333
    Summary
    Downregulated twofold by GSNO in defined medium (aerobic). [More information is available at EcoGene: EG11327]. CodB is a cytosine transporter which probably functions as a cytosine/proton symporter. [More information is available at EcoCyc: EG11327].
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    Genomic context

    Sequence:
    NC_000913.3 (354922..356181)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene 2-methylcitrate dehydratase Neighboring gene propionyl-CoA synthetase Neighboring gene cytosine/isoguanine deaminase Neighboring gene DNA-binding transcriptional dual regulator CynR Neighboring gene carbonic anhydrase 1

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables cytosine transmembrane transporter activity EXP
    Inferred from Experiment
    more info
    PubMed 
    enables cytosine transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables solute:proton symporter activity RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cytosine metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cytosine transport EXP
    Inferred from Experiment
    more info
    PubMed 
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      354922..356181
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414870.1 cytosine transporter [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414870.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5B9AKZ0
      Conserved Domains (1) summary
      PRK11017
      Location:9411
      codB; cytosine permease; Provisional