U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    puuC gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947003, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    puuC
    Official Full Name
    gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase
    Primary source
    ECOCYC:EG10036
    Locus tag
    b1300
    See related
    ASAP:ABE-0004376
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    aldH; ECK1295
    Summary
    PuuC is inferred to be the -glutamyl--aminobutyraldehyde dehydrogenase in a putrescine utilization pathway; together with PuuB, -glutamyl--aminobutyrate is produced from -glutamylputrescine . [More information is available at EcoCyc: EG10036].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (1362743..1364230)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene gamma-glutamyl-gamma-aminobutyrate hydrolase Neighboring gene DNA-binding transcriptional repressor PuuR Neighboring gene gamma-glutamylputrescine oxidase Neighboring gene 4-aminobutyrate aminotransferase PuuE

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Cloning, expression, and characterization of an aldehyde dehydrogenase from Escherichia coli K-12 that utilizes 3-Hydroxypropionaldehyde as a substrate. Jo JE, et al. Appl Microbiol Biotechnol, 2008 Nov. PMID 18668238
    2. The RIB element in the goaG-pspF intergenic region of Escherichia coli. Jovanovic G, et al. J Bacteriol, 1997 May. PMID 9150200, Free PMC Article
    3. Cloning an Escherichia coli gene encoding a protein remarkably similar to mammalian aldehyde dehydrogenases. Heim R, et al. Gene, 1991 Mar 1. PMID 1840553
    4. A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12. Kurihara S, et al. J Biol Chem, 2005 Feb 11. PMID 15590624
    5. Transcriptional response of Escherichia coli to external copper. Yamamoto K, et al. Mol Microbiol, 2005 Apr. PMID 15773991

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AldH preferred NAD+ over NADP+ as a cofactor for the oxidation.
      Title: Cloning, expression, and characterization of an aldehyde dehydrogenase from Escherichia coli K-12 that utilizes 3-Hydroxypropionaldehyde as a substrate.
    Submit: New GeneRIF Correction

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables aldehyde dehydrogenase (NAD+) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables aldehyde dehydrogenase (NADP+) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables aldehyde dehydrogenase [NAD(P)+] activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables aldehyde dehydrogenase [NAD(P)+] activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in putrescine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within putrescine catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase
    NP_415816.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1362743..1364230
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415816.1 gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415816.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A3L9HZX9, A0A7H9SFV4
      Conserved Domains (1) summary
      PRK09847
      Location:1 → 494
      PRK09847; gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Provisional
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.