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    cysC adenylyl-sulfate kinase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947221, updated on 3-Dec-2024

    Summary

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    Official Symbol
    cysC
    Official Full Name
    adenylyl-sulfate kinase
    Primary source
    ECOCYC:EG10185
    Locus tag
    b2750
    See related
    ASAP:ABE-0009023
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2745
    Summary
    The enzyme exists predominantly as a homodimer, but a tetrameric form exists when the enzyme is dephosphorylated. [More information is available at EcoCyc: EG10185].
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    Genomic context

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    Sequence:
    NC_000913.3 (2873387..2873992, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene cell division protein FtsB Neighboring gene DUF3561 domain-containing inner membrane protein YgbE Neighboring gene sulfate adenylyltransferase subunit 1 Neighboring gene sulfate adenylyltransferase subunit 2 Neighboring gene alkaline phosphatase isozyme conversion protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mechanistic studies of Escherichia coli adenosine-5'-phosphosulfate kinase. Satishchandran C, et al. Arch Biochem Biophys, 2000 Jun 15. PMID 10860538
    2. Adenosine-5'-phosphosulfate kinase from Escherichia coli K12. Purification, characterization, and identification of a phosphorylated enzyme intermediate. Satishchandran C, et al. J Biol Chem, 1989 Sep 5. PMID 2549047
    3. Characterization of the phosphorylated enzyme intermediate formed in the adenosine 5'-phosphosulfate kinase reaction. Satishchandran C, et al. Biochemistry, 1992 Dec 1. PMID 1332767
    4. Lambda transducing phage and clones carrying genes of the cysJIHDC gene cluster of Escherichia coli K12. Hunt CL, et al. J Gen Microbiol, 1987 Oct. PMID 2966849
    5. The DNA sequence of the sulfate activation locus from Escherichia coli K-12. Leyh TS, et al. J Biol Chem, 1992 May 25. PMID 1316900

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on mature peptide
      Title: The DNA sequence of the sulfate activation locus from Escherichia coli K-12.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables adenylylsulfate kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables adenylylsulfate kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables adenylylsulfate kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables identical protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in hydrogen sulfide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sulfate assimilation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sulfate assimilation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    adenylyl-sulfate kinase
    NP_417230.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2873387..2873992 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417230.1 adenylyl-sulfate kinase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417230.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8T5ZGN1
      Conserved Domains (1) summary
      PRK03846
      Location:5 → 201
      PRK03846; adenylylsulfate kinase; Provisional
    Nucleotide Protein
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