U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    zupT divalent metal ion transporter ZupT [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947035, updated on 17-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    zupT
    Official Full Name
    divalent metal ion transporter ZupT
    Primary source
    ECOCYC:EG11167
    Locus tag
    b3040
    See related
    ASAP:ABE-0009977
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3031; ygiE
    Summary
    The zupT synonym ygiE was mistakenly used to refer to ygjE in the abstract of Oshima, 2006 (see the ygjE bibliography). [More information is available at EcoGene: EG11167]. ZupT is a member of the ZIP family of divalent metal cation transporters, and is predicted to have 8 transmembrane domains. [More information is available at EcoCyc: EG11167].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (3182550..3183323)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative acid--amine ligase YgiC Neighboring gene 4,5-DOPA dioxygenase extradiol Neighboring gene protein YqiD Neighboring gene 3,4-dihydroxy-2-butanone-4-phosphate synthase

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The Zinc and Iron Binuclear Transport Center of ZupT, a ZIP Transporter from Escherichia coli. Roberts CS, et al. Biochemistry, 2021 Dec 7. PMID 34793140
    2. Point mutations change specificity and kinetics of metal uptake by ZupT from Escherichia coli. Taudte N, et al. Biometals, 2010 Aug. PMID 20225068
    3. Roles of the extraintestinal pathogenic Escherichia coli ZnuACB and ZupT zinc transporters during urinary tract infection. Sabri M, et al. Infect Immun, 2009 Mar. PMID 19103764, Free PMC Article
    4. The metal permease ZupT from Escherichia coli is a transporter with a broad substrate spectrum. Grass G, et al. J Bacteriol, 2005 Mar. PMID 15716430, Free PMC Article
    5. Nucleotide sequence of a region duplicated in Escherichia coli toc mutants. Yang TP, et al. Biochim Biophys Acta, 1992 Mar 24. PMID 1314093

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data provide information on the substrate specificity of ZupT and further insight into the function of ZupT as a bacterial member of the vastly distributed and important ZIP family.
      Title: Point mutations change specificity and kinetics of metal uptake by ZupT from Escherichia coli.
    2. Znu and ZupT are required for growth of Escherichia coli K-12 in zinc limited-conditions
      Title: Roles of the extraintestinal pathogenic Escherichia coli ZnuACB and ZupT zinc transporters during urinary tract infection.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ferrous iron transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ferrous iron transmembrane transporter activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cobalt ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in iron ion import across plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in iron ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in metal ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in zinc ion import across plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in zinc ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in zinc ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in zinc ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in zinc ion transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    divalent metal ion transporter ZupT

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3182550..3183323
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417512.1 divalent metal ion transporter ZupT [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417512.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A7A6ZQ24
      Conserved Domains (1) summary
      PRK04201
      Location:1 → 252
      PRK04201; zinc transporter ZupT; Provisional
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.