deoA thymidine phosphorylase [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Official Symbol: deoA
Official Full Name: thymidine phosphorylase
Primary source: ECOCYC:EG10219
Locus tag: b4382
See related: ASAP:ABE-0014374
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: ECK4374; TP; tpp; ttg
NEW: Try the new Gene table
Try the new Transcript table

NC_000913.3 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Data show that thymidine phosphorylase enzymatic phosphorolysis of thymidine was reduced by 5-fluoruracil derivatives.
Title: Kinetics and mechanistic study of competitive inhibition of thymidine phosphorylase by 5-fluoruracil derivatives.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables 1,4-alpha-oligoglucan phosphorylase activity	IEA Inferred from Electronic Annotation more info
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables pentosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables thymidine phosphorylase activity	IBA Inferred from Biological aspect of Ancestor more info
enables thymidine phosphorylase activity	IDA Inferred from Direct Assay more info	PubMed
enables thymidine phosphorylase activity	IEA Inferred from Electronic Annotation more info
enables thymidine phosphorylase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA damage response	IEP Inferred from Expression Pattern more info	PubMed
involved_in pyrimidine nucleobase metabolic process	IEA Inferred from Electronic Annotation more info
involved_in pyrimidine nucleoside metabolic process	IEA Inferred from Electronic Annotation more info
involved_in pyrimidine nucleoside metabolic process	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in thymidine metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed
located_in membrane	HDA more info	PubMed

NP_418799.1

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain