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    nrfE putative cytochrome c-type biogenesis protein NrfE [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948579, updated on 17-Dec-2024

    Summary

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    Official Symbol
    nrfE
    Official Full Name
    putative cytochrome c-type biogenesis protein NrfE
    Primary source
    ECOCYC:EG11948
    Locus tag
    b4074
    See related
    ASAP:ABE-0013350
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4067; yjcL
    Summary
    NrfE is a membrane-spanning protein that is essential for NirA activity. [More information is available at EcoCyc: EG11948].
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    Genomic context

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    Sequence:
    NC_000913.3 (4291512..4293170)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene periplasmic nitrite reductase penta-heme c-type cytochrome Neighboring gene putative menaquinol-cytochrome c reductase 4Fe-4S subunit Neighboring gene putative menaquinol-cytochrome c reductase subunit NrfD Neighboring gene putative formate-dependent nitrite reductase complex subunit NrfF Neighboring gene putative formate-dependent nitrite reductase complex subunit NrfG Neighboring gene glutamate/aspartate : H(+) symporter GltP

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of the formate dehydrogenases and genetic determinants of formate-dependent nitrite reduction by Escherichia coli K12. Darwin A, et al. J Gen Microbiol, 1993 Aug. PMID 8409924
    2. Involvement of products of the nrfEFG genes in the covalent attachment of haem c to a novel cysteine-lysine motif in the cytochrome c552 nitrite reductase from Escherichia coli. Eaves DJ, et al. Mol Microbiol, 1998 Apr. PMID 9593308
    3. Nitric oxide formation by Escherichia coli. Dependence on nitrite reductase, the NO-sensing regulator Fnr, and flavohemoglobin Hmp. Corker H, et al. J Biol Chem, 2003 Aug 22. PMID 12783887
    4. The role of the genes nrf EFG and ccmFH in cytochrome c biosynthesis in Escherichia coli. Grovc J, et al. Mol Gen Genet, 1996 Sep 13. PMID 8842153
    5. Nitric oxide-sensing mechanisms in Escherichia coli. Spiro S. Biochem Soc Trans, 2006 Feb. PMID 16417522

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables heme transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytochrome complex assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in heme transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative cytochrome c-type biogenesis protein NrfE

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4291512..4293170
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418498.1 putative cytochrome c-type biogenesis protein NrfE [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418498.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A1X3HYY0, A0A366VPV2, A0A828Q2H5, A0A8S7RXR1, A0AAD2NUX7, B7NG17
      Conserved Domains (1) summary
      PRK10369
      Location:1 → 552
      PRK10369; heme lyase subunit NrfE; Provisional
    Nucleotide Protein
    Heading Accession and Version

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