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    sapF putrescine ABC exporter ATP binding protein SapF [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945335, updated on 3-Dec-2024

    Summary

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    Official Symbol
    sapF
    Official Full Name
    putrescine ABC exporter ATP binding protein SapF
    Primary source
    ECOCYC:EG12305
    Locus tag
    b1290
    See related
    ASAP:ABE-0004339
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1285
    Summary
    Characterized initially in Salmonella. [More information is available at EcoGene: EG12305]. SapABCDF (Sensitive to antimicrobial peptides) is a member of the ATP Binding Cassette (ABC) transporter superfamily . [More information is available at EcoCyc: EG12305].
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    Genomic context

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    Sequence:
    NC_000913.3 (1351828..1352634, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene enoyl-[acyl-carrier-protein] reductase Neighboring gene DUF559 domain-containing protein YcjD Neighboring gene putrescine ABC exporter ATP binding protein SapD Neighboring gene putrescine ABC exporter membrane protein SapC Neighboring gene putrescine ABC exporter membrane subunit SapB Neighboring gene putative periplasmic binding protein SapA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Salmonella protein that is required for resistance to antimicrobial peptides and transport of potassium. Parra-Lopez C, et al. EMBO J, 1994 Sep 1. PMID 8076592, Free PMC Article
    2. Resistance to host antimicrobial peptides is necessary for Salmonella virulence. Groisman EA, et al. Proc Natl Acad Sci U S A, 1992 Dec 15. PMID 1465423, Free PMC Article
    3. Identification of the ABC protein SapD as the subunit that confers ATP dependence to the K+-uptake systems Trk(H) and Trk(G) from Escherichia coli K-12. Harms C, et al. Microbiology (Reading), 2001 Nov. PMID 11700350
    4. Requirement of a large K+-uptake capacity and of extracytoplasmic protease activity for protamine resistance of Escherichia coli. Stumpe S, et al. Arch Microbiol, 1997 Feb-Mar. PMID 9133319
    5. ATP-binding cassette transporters in Escherichia coli. Moussatova A, et al. Biochim Biophys Acta, 2008 Sep. PMID 18634750

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables putrescine transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in peptide transport NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within putrescine transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of ATP-binding cassette (ABC) transporter complex RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putrescine ABC exporter ATP binding protein SapF

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1351828..1352634 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415806.1 putrescine ABC exporter ATP binding protein SapF [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415806.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376DHY0
      Conserved Domains (1) summary
      PRK15112
      Location:2 → 268
      PRK15112; peptide ABC transporter ATP-binding protein SapF
    Nucleotide Protein
    Heading Accession and Version

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