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    glpX fructose-1,6-bisphosphatase 2 [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948424, updated on 3-Dec-2024

    Summary

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    Official Symbol
    glpX
    Official Full Name
    fructose-1,6-bisphosphatase 2
    Primary source
    ECOCYC:EG11517
    Locus tag
    b3925
    See related
    ASAP:ABE-0012821
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3917
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    Genomic context

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    Sequence:
    NC_000913.3 (4114569..4115579, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene universal stress protein D Neighboring gene flavodoxin/ferredoxin-NADP(+) reductase Neighboring gene glycerol kinase Neighboring gene glycerol facilitator

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isolation and characterization of methyl viologen-sensitive mutants of Escherichia coli K-12. Morimyo M. J Bacteriol, 1988 May. PMID 2834327, Free PMC Article
    2. Mutational analysis of the Escherichia coli glpFK region with Tn5 mutagenesis and the polymerase chain reaction. Lupski JR, et al. J Bacteriol, 1990 Oct. PMID 2170343, Free PMC Article
    3. Structural and biochemical characterization of the type II fructose-1,6-bisphosphatase GlpX from Escherichia coli. Brown G, et al. J Biol Chem, 2009 Feb 6. PMID 19073594, Free PMC Article
    4. Molecular analysis of the glpFKX regions of Escherichia coli and Shigella flexneri. Truniger V, et al. J Bacteriol, 1992 Nov. PMID 1400248, Free PMC Article
    5. Structure and regulation of the glpFK operon encoding glycerol diffusion facilitator and glycerol kinase of Escherichia coli K-12. Weissenborn DL, et al. J Biol Chem, 1992 Mar 25. PMID 1372899

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables fructose 1,6-bisphosphate 1-phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables fructose 1,6-bisphosphate 1-phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables fructose 1,6-bisphosphate 1-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables manganese ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein homodimerization activity IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in fructose 1,6-bisphosphate metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in gluconeogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in gluconeogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in glycerol metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    fructose-1,6-bisphosphatase 2
    NP_418360.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4114569..4115579 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418360.1 fructose-1,6-bisphosphatase 2 [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418360.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8T6BU79
      Conserved Domains (1) summary
      TIGR00330
      Location:2 → 322
      glpX; fructose-1,6-bisphosphatase, class II
    Nucleotide Protein
    Heading Accession and Version

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