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    gfcE putative exopolysaccharide export lipoprotein GfcE [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945586, updated on 3-Dec-2024

    Summary

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    Official Symbol
    gfcE
    Official Full Name
    putative exopolysaccharide export lipoprotein GfcE
    Primary source
    ECOCYC:G6504
    Locus tag
    b0983
    See related
    ASAP:ABE-0003317
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0974; yccZ
    Summary
    GfcE may form a channel through the outer membrane for transport of the O-antigen capsule polysaccharides. yccZ and wza are paralogs. [More information is available at EcoGene: EG13728]. The operon encoding YmcD, YmcC, YmcB, YmcA, YzzZ, Etp, and Etk was characterized in the enteropathogenic Escherichia coli strain O127:H6. [More information is available at EcoCyc: G6504].
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    Genomic context

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    Sequence:
    NC_000913.3 (1044664..1045803, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene periplasmic phosphoanhydride phosphatase/multiple inositol-polyphosphate phosphatase Neighboring gene protein-tyrosine kinase Etk Neighboring gene phosphotyrosine-protein phosphatase Etp Neighboring gene putative lipoprotein GfcD Neighboring gene capsule biosynthesis GfcC family protein Neighboring gene lipoprotein GfcB

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. PELDOR spectroscopy distance fingerprinting of the octameric outer-membrane protein Wza from Escherichia coli. Hagelueken G, et al. Angew Chem Int Ed Engl, 2009. PMID 19294709, Free PMC Article
    2. Wza the translocon for E. coli capsular polysaccharides defines a new class of membrane protein. Dong C, et al. Nature, 2006 Nov 9. PMID 17086202, Free PMC Article
    3. Computer-based analyses of the protein constituents of transport systems catalysing export of complex carbohydrates in bacteria. Paulsen IT, et al. Microbiology (Reading), 1997 Aug. PMID 9274022
    4. Biosynthesis and assembly of capsular polysaccharides in Escherichia coli. Whitfield C. Annu Rev Biochem, 2006. PMID 16756484
    5. BOMP: a program to predict integral beta-barrel outer membrane proteins encoded within genomes of Gram-negative bacteria. Berven FS, et al. Nucleic Acids Res, 2004 Jul 1. PMID 15215418, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables polysaccharide transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables polysaccharide transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables porin activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in polysaccharide transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cell outer membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of pore complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative exopolysaccharide export lipoprotein GfcE

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1044664..1045803 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415503.1 putative exopolysaccharide export lipoprotein GfcE [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415503.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8T5YK45
      Conserved Domains (1) summary
      PRK15078
      Location:1 → 377
      PRK15078; polysaccharide export protein Wza; Provisional
    Nucleotide Protein
    Heading Accession and Version

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