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    yccA modulator of FtsH protease [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946016, updated on 3-Dec-2024

    Summary

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    Official Symbol
    yccA
    Official Full Name
    modulator of FtsH protease
    Primary source
    ECOCYC:EG11113
    Locus tag
    b0970
    See related
    ASAP:ABE-0003280
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0961
    Summary
    YccA is a substrate or modulator of FtsH-mediated proteolysis. [More information is available at EcoCyc: EG11113].
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    Genomic context

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    Sequence:
    NC_000913.3 (1030759..1031418, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene 23S rRNA m(5)C1962 methyltransferase Neighboring gene acylphosphatase Neighboring gene sulfur transfer protein TusE Neighboring gene tRNA-Ser Neighboring gene hydrogenase 1 small subunit Neighboring gene hydrogenase 1 large subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. BAX Inhibitor-1, an ancient cell death suppressor in animals and plants with prokaryotic relatives. Hückelhoven R. Apoptosis, 2004 May. PMID 15258461
    2. The E. coli divE mutation, which differentially inhibits synthesis of certain proteins, is in tRNASer1. Tamura F, et al. EMBO J, 1984 May. PMID 6376117, Free PMC Article
    3. Dislocation of membrane proteins in FtsH-mediated proteolysis. Kihara A, et al. EMBO J, 1999 Jun 1. PMID 10357810, Free PMC Article
    4. Length recognition at the N-terminal tail for the initiation of FtsH-mediated proteolysis. Chiba S, et al. EMBO Rep, 2000 Jul. PMID 11256624, Free PMC Article
    5. Cell biology. Lethal traffic jam. Breukink E. Science, 2009 Aug 7. PMID 19661407

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. study of the effects of antibiotics and the proto-oncogene homolog YccA on destruction of SecY
      Title: Effects of antibiotics and a proto-oncogene homolog on destruction of protein translocator SecY.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables calcium channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in calcium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within regulation of proteolysis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    modulator of FtsH protease

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1030759..1031418 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415490.1 modulator of FtsH protease [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415490.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0AAN4AEY9
      Conserved Domains (1) summary
      PRK10447
      Location:1 → 219
      PRK10447; FtsH protease modulator YccA
    Nucleotide Protein
    Heading Accession and Version

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