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    CG2972 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31943, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG2972provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030177
    Locus tag
    Dmel_CG2972
    See related
    AllianceGenome:FB:FBgn0030177
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG2972; NOB1
    Summary
    Predicted to enable RNA endonuclease activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to be part of preribosome, small subunit precursor. Orthologous to human NOB1 (NIN1 (RPN12) binding protein 1 homolog). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG2972 in Genome Data Viewer
    Location:
    9B1-9B1; 1-31 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (10083154..10085050)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (9977187..9979083)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45602 Neighboring gene ZAP3 Neighboring gene NAD(P)HX epimerase Neighboring gene RhoU Neighboring gene antisense RNA:CR44894 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulation of Ribosome Biogenesis and Protein Synthesis Controls Germline Stem Cell Differentiation. Sanchez CG, et al. Cell Stem Cell, 2016 Feb 4. PMID 26669894, Free PMC Article
    2. The phospho-docking protein 14-3-3 regulates microtubule-associated proteins in oocytes including the chromosomal passenger Borealin. Repton C, et al. PLoS Genet, 2022 Jun. PMID 35666772, Free PMC Article
    3. Transcriptional response to dietary restriction in Drosophila melanogaster. Ding F, et al. J Insect Physiol, 2014 Oct. PMID 24819200, Free PMC Article
    4. Wolbachia and Virus Alter the Host Transcriptome at the Interface of Nucleotide Metabolism Pathways. Lindsey ARI, et al. mBio, 2021 Feb 9. PMID 33563832, Free PMC Article
    5. An Integrative Analysis of the InR/PI3K/Akt Network Identifies the Dynamic Response to Insulin Signaling. Vinayagam A, et al. Cell Rep, 2016 Sep 13. PMID 27626673, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA endonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in maturation of SSU-rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosomal small subunit biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of preribosome, small subunit precursor IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG2972-PA
    CG2972-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      10083154..10085050
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298143.1 → NP_001285072.1  uncharacterized protein Dmel_CG2972, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285072.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W2Y4
      Conserved Domains (3) summary
      cd09876
      Location:11 → 120
      PIN_Nob1; PIN domain of eukaryotic ribosome assembly factor Nob1 and archaeal UPF0129 protein Ta0041-like homologs
      pfam08772
      Location:319 → 390
      NOB1_Zn_bind; Nin one binding (NOB1) Zn-ribbon like
      cl14812
      Location:279 → 355
      PIN_SF; PIN (PilT N terminus) domain: Superfamily

    2. NM_132375.3 → NP_572603.1  uncharacterized protein Dmel_CG2972, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572603.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W2Y4
      Related
      FBpp0071365
      Conserved Domains (3) summary
      cd09876
      Location:11 → 120
      PIN_Nob1; PIN domain of eukaryotic ribosome assembly factor Nob1 and archaeal UPF0129 protein Ta0041-like homologs
      pfam08772
      Location:319 → 390
      NOB1_Zn_bind; Nin one binding (NOB1) Zn-ribbon like
      cl14812
      Location:279 → 355
      PIN_SF; PIN (PilT N terminus) domain: Superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W2Y4 Q9W2Y4

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