Pglym87 Phosphoglyceromutase 87 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Pglym87provided by FlyBase
Official Full Name: Phosphoglyceromutase 87provided by FlyBase
Primary source: FLYBASE:FBgn0011270
Locus tag: Dmel_CG17645
See related: AllianceGenome:FB:FBgn0011270
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG17645; Dmel\CG17645; Pglym; pglym87
Summary: Predicted to enable 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity and bisphosphoglycerate mutase activity. Predicted to be involved in canonical glycolysis and gluconeogenesis. Predicted to be active in cytosol. Is expressed in adult head; elongation stage spermatid; primary spermatocyte; and spermatozoon. Human ortholog(s) of this gene implicated in myoglobinuria. Orthologous to human PGAM1 (phosphoglycerate mutase 1); PGAM2 (phosphoglycerate mutase 2); and PGAM4 (phosphoglycerate mutase family member 4). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: 87B3-87B3; 3-52 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (12231645..12232729, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (8057367..8058451, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by FlyBase

Function	Evidence Code	Pubs
enables 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity	ISS Inferred from Sequence or Structural Similarity more info
enables bisphosphoglycerate mutase activity	ISS Inferred from Sequence or Structural Similarity more info
enables intramolecular phosphotransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in canonical glycolysis	ISS Inferred from Sequence or Structural Similarity more info
involved_in gluconeogenesis	ISS Inferred from Sequence or Structural Similarity more info
involved_in glycolytic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytosol	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: phosphoglyceromutase 87

Names: CG17645-PA; Pglym87-PA

NP_652041.2

EC 5.4.2.-

EC 5.4.2.11

EC 5.4.2.4

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NT_033777.3 Reference assembly

Range

12231645..12232729 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_143784.3 → NP_652041.2 phosphoglyceromutase 87 [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_652041.2

Status: REVIEWED

UniProtKB/TrEMBL

Q8MR44, Q9VGB6

Related

FBpp0082089

Conserved Domains (1) summary

PRK14115
Location:42 → 292

gpmA; phosphoglyceromutase; Provisional