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    Ent1 Equilibrative nucleoside transporter 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33207, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ent1provided by FlyBase
    Official Full Name
    Equilibrative nucleoside transporter 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0031250
    Locus tag
    Dmel_CG11907
    See related
    AllianceGenome:FB:FBgn0031250
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:fe2G2; CG11907; dENT1; Dmel\CG11907; DmEnt1; DmENT1; ent1; ENT1
    Summary
    Predicted to enable nucleoside transmembrane transporter activity. Predicted to be involved in nucleoside transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in adult head and organism. Human ortholog(s) of this gene implicated in histiocytosis-lymphadenopathy plus syndrome. Orthologous to human SLC29A1 (solute carrier family 29 member 1 (Augustine blood group)); SLC29A2 (solute carrier family 29 member 2); and SLC29A3 (solute carrier family 29 member 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Ent1 in Genome Data Viewer
    Location:
    21C1-21C1; 2-0.7 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (355565..357874, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (355565..357874, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Phospholipase C at 21C Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45367 Neighboring gene antisense RNA:CR45366 Neighboring gene aristaless Neighboring gene long non-coding RNA:CR43718

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables nucleoside transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables nucleoside transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleoside transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in nucleoside transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in nucleoside transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in nucleoside transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    equilibrative nucleoside transporter 1
    Names
    CG11907-PA
    CG11907-PB
    CG11907-PC
    Ent1-PA
    Ent1-PB
    Ent1-PC
    anon-fast-evolving-2G2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      355565..357874 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001272891.1NP_001259820.1  equilibrative nucleoside transporter 1, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259820.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95RN3, Q9NHZ1, Q9VPP0
      Conserved Domains (1) summary
      cl15430
      Location:69476
      Nucleoside_tran; Nucleoside transporter
    2. NM_134675.5NP_608519.2  equilibrative nucleoside transporter 1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608519.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95RN3, Q9NHZ1, Q9VPP0
      Related
      FBpp0077754
      Conserved Domains (1) summary
      cl15430
      Location:69476
      Nucleoside_tran; Nucleoside transporter
    3. NM_164381.2NP_722628.1  equilibrative nucleoside transporter 1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722628.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95RN3, Q9NHZ1, Q9VPP0
      Related
      FBpp0077753
      Conserved Domains (1) summary
      cl15430
      Location:69476
      Nucleoside_tran; Nucleoside transporter