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    CG7523 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42125, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7523provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038533
    Locus tag
    Dmel_CG7523
    See related
    AllianceGenome:FB:FBgn0038533
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7523
    Summary
    Predicted to be active in late endosome and lysosomal membrane. Is expressed in adult head and adult heart. Orthologous to human TMEM192 (transmembrane protein 192). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7523 in Genome Data Viewer
    Location:
    90C1-90C1; 3-61 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (17669144..17670895, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (13494866..13496617, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene transfer RNA:Alanine-AGC 2-10 Neighboring gene uncharacterized protein Neighboring gene Monopolar spindle 1 Neighboring gene aluminum tubes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Off-target piRNA gene silencing in Drosophila melanogaster rescued by a transposable element insertion. Miller DE, et al. PLoS Genet, 2023 Feb. PMID 36809339, Free PMC Article
    2. The meiotic defects of mutants in the Drosophila mps1 gene reveal a critical role of Mps1 in the segregation of achiasmate homologs. Gilliland WD, et al. Curr Biol, 2005 Apr 12. PMID 15823541
    3. The mitotic arrest in response to hypoxia and of polar bodies during early embryogenesis requires Drosophila Mps1. Fischer MG, et al. Curr Biol, 2004 Nov 23. PMID 15556864
    4. An amino acid polymorphism in the couch potato gene forms the basis for climatic adaptation in Drosophila melanogaster. Schmidt PS, et al. Proc Natl Acad Sci U S A, 2008 Oct 21. PMID 18852464, Free PMC Article
    5. Genome-wide examination of the transcriptional response to ecdysteroids 20-hydroxyecdysone and ponasterone A in Drosophila melanogaster. Gonsalves SE, et al. BMC Genomics, 2011 Sep 29. PMID 21958154, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    is_active_in late endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in lysosomal membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7523-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      17669144..17670895 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142386.4 → NP_650643.2  uncharacterized protein Dmel_CG7523 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650643.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6NL61, Q9VEH2
      Related
      FBpp0082923
      Conserved Domains (1) summary
      pfam14802
      Location:23 → 247
      TMEM192; TMEM192 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q95SY0 Q95SY0
    Q9VEH2 Q9VEH2

    Gene LinkOut

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