slp2 sloppy paired 2 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: slp2provided by FlyBase
Official Full Name: sloppy paired 2provided by FlyBase
Primary source: FLYBASE:FBgn0004567
Locus tag: Dmel_CG2939
See related: AllianceGenome:FB:FBgn0004567
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG2939; Dmel\CG2939; Dmslp2; FD7; FoxG; Sloppy-paired; slp; Slp; SLP; Slp2
Summary: Predicted to enable sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including anlage in statu nascendi; antennal primordium; ganglia; head epidermis primordium; and head segment. Orthologous to human FOXG1 (forkhead box G1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (3836840..3839185)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (3836840..3839185)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

slp1 and slp2 are coordinately regulated by 8 stripe enhancers surrounding slp1.
Title: Regulation of a duplicated locus: Drosophila sloppy paired is replete with functionally overlapping enhancers.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info
enables sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info
enables sequence-specific double-stranded DNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info