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    Tsp97E Tetraspanin 97E [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43241, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tsp97Eprovided by FlyBase
    Official Full Name
    Tetraspanin 97Eprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039465
    Locus tag
    Dmel_CG6323
    See related
    AllianceGenome:FB:FBgn0039465
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG6323; Dm.Tsp97E; Dmel\CG6323; Tspan31
    Summary
    Predicted to be located in membrane. Is expressed in adult head; embryonic brain; larval ventral nerve cord; and organism. Orthologous to human TSPAN13 (tetraspanin 13) and TSPAN31 (tetraspanin 31). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Tsp97E in Genome Data Viewer
    Location:
    97D11-97D11; 3-92 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (26961064..26964817, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (22786786..22790539, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Spag1 axonemal dynein assembly factor Neighboring gene uncharacterized protein Neighboring gene Gustatory receptor 97a Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evolutionary dynamics of U12-type spliceosomal introns. Lin CF, et al. BMC Evol Biol, 2010 Feb 17. PMID 20163699, Free PMC Article
    2. A Drosophila model of spinal muscular atrophy uncouples snRNP biogenesis functions of survival motor neuron from locomotion and viability defects. Praveen K, et al. Cell Rep, 2012 Jun 28. PMID 22813737, Free PMC Article
    3. An SMN-dependent U12 splicing event essential for motor circuit function. Lotti F, et al. Cell, 2012 Oct 12. PMID 23063131, Free PMC Article
    4. Identification of an evolutionarily divergent U11 small nuclear ribonucleoprotein particle in Drosophila. Schneider C, et al. Proc Natl Acad Sci U S A, 2004 Jun 29. PMID 15210936, Free PMC Article
    5. Gene expression profiling of U12-type spliceosome mutant Drosophila reveals widespread changes in metabolic pathways. Pessa HK, et al. PLoS One, 2010 Oct 11. PMID 20949011, Free PMC Article

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tetraspanin 97E
    Names
    CG6323-PA
    CG6323-PD
    CG6323-PE
    CG6323-PG
    CG6323-PH
    Tetraspanin97E
    Tsp97E-PA
    Tsp97E-PD
    Tsp97E-PE
    Tsp97E-PG
    Tsp97E-PH

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      26961064..26964817 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300621.1 → NP_001287550.1  tetraspanin 97E, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287550.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G2J606, Q9VB99
      Conserved Domains (2) summary
      cl02781
      Location:121 → 177
      tetraspanin_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...
      pfam00335
      Location:7 → 204
      Tetraspannin; Tetraspanin family

    2. NM_170297.3 → NP_733176.2  tetraspanin 97E, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733176.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7Z0Q9, G2J606, Q8IMQ7
      Conserved Domains (2) summary
      cl02781
      Location:121 → 177
      tetraspanin_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...
      pfam00335
      Location:7 → 210
      Tetraspannin; Tetraspanin family

    3. NM_001276073.1 → NP_001263002.1  tetraspanin 97E, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001263002.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G2J606, Q9VB99
      Conserved Domains (2) summary
      cl02781
      Location:121 → 177
      tetraspanin_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...
      pfam00335
      Location:7 → 204
      Tetraspannin; Tetraspanin family

    4. NM_001144643.3 → NP_001138115.2  tetraspanin 97E, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001138115.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7Z0Q9, G2J606, Q8IMQ7
      Conserved Domains (2) summary
      cl02781
      Location:121 → 177
      tetraspanin_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...
      pfam00335
      Location:7 → 210
      Tetraspannin; Tetraspanin family

    5. NM_079800.3 → NP_524524.1  tetraspanin 97E, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524524.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G2J606, Q9VB99
      Related
      FBpp0084454
      Conserved Domains (2) summary
      cl02781
      Location:121 → 177
      tetraspanin_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...
      pfam00335
      Location:7 → 204
      Tetraspannin; Tetraspanin family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IMQ7 Q8IMQ7
    Q9VB99 Q9VB99

    Gene LinkOut

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