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    dpr14 defective proboscis extension response 14 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31702, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dpr14provided by FlyBase
    Official Full Name
    defective proboscis extension response 14provided by FlyBase
    Primary source
    FLYBASE:FBgn0029974
    Locus tag
    Dmel_CG10946
    See related
    AllianceGenome:FB:FBgn0029974
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10946; CT30653; Dmel\CG10946; Dpr-14; Dpr14
    Summary
    Involved in synapse organization. Predicted to be located in plasma membrane. Predicted to be active in neuron projection membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See dpr14 in Genome Data Viewer
    Location:
    7C2-7C2; 1-21 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (7903704..7908286, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (7797737..7802319, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene Ribosomal protein S6 Neighboring gene by S6 Neighboring gene spidey Neighboring gene snazarus

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. BEAF regulates cell-cycle genes through the controlled deposition of H3K9 methylation marks into its conserved dual-core binding sites. Emberly E, et al. PLoS Biol, 2008 Dec 23. PMID 19108610, Free PMC Article
    2. Defective proboscis extension response (DPR), a member of the Ig superfamily required for the gustatory response to salt. Nakamura M, et al. J Neurosci, 2002 May 1. PMID 11978823, Free PMC Article
    3. Neural immunoglobulin superfamily interaction networks. Zinn K, et al. Curr Opin Neurobiol, 2017 Aug. PMID 28558267, Free PMC Article
    4. Systematic expression profiling of Dpr and DIP genes reveals cell surface codes in Drosophila larval motor and sensory neurons. Wang Y, et al. Development, 2022 May 15. PMID 35502740, Free PMC Article
    5. Computational Assessment of Protein-Protein Binding Specificity within a Family of Synaptic Surface Receptors. Nandigrami P, et al. J Phys Chem B, 2022 Oct 6. PMID 35787023

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in sensory perception of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in synapse organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in synapse organization IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in neuron projection membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    defective proboscis extension response 14
    Names
    CG10946-PA
    CG10946-PB
    dpr14-PA
    dpr14-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      7903704..7908286 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001258644.2 → NP_001245573.1  defective proboscis extension response 14, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245573.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q961K3, Q9W3N2
      Conserved Domains (3) summary
      cd00096
      Location:201 → 274
      Ig; Immunoglobulin domain
      smart00410
      Location:191 → 279
      IG_like; Immunoglobulin like
      cl11960
      Location:84 → 169
      Ig; Immunoglobulin domain

    2. NM_132191.3 → NP_572419.1  defective proboscis extension response 14, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572419.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q961K3, Q9W3N2
      Related
      FBpp0071086
      Conserved Domains (3) summary
      cd00096
      Location:201 → 274
      Ig; Immunoglobulin domain
      smart00410
      Location:191 → 279
      IG_like; Immunoglobulin like
      cl11960
      Location:84 → 169
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W3N2 Q9W3N2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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