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    CG15237 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35591, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG15237provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033104
    Locus tag
    Dmel_CG15237
    See related
    AllianceGenome:FB:FBgn0033104
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    APC15; Dmel\CG15237
    Summary
    Predicted to be involved in regulation of mitotic cell cycle spindle assembly checkpoint. Predicted to be part of anaphase-promoting complex. Orthologous to human ANAPC15 (anaphase promoting complex subunit 15). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG15237 in Genome Data Viewer
    Location:
    42D4-42D4; 2-55 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (6809044..6809766, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (2696549..2697271, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Exchange protein directly activated by cAMP Neighboring gene Cytochrome P450 6a2 Neighboring gene Succinate dehydrogenase, subunit B (iron-sulfur) Neighboring gene ubiquitin like Neighboring gene klaroid

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The APC/C Coordinates Retinal Differentiation with G1 Arrest through the Nek2-Dependent Modulation of Wingless Signaling. Martins T, et al. Dev Cell, 2017 Jan 9. PMID 28041905, Free PMC Article
    2. SOD1 activity threshold and TOR signalling modulate VAP(P58S) aggregation via reactive oxygen species-induced proteasomal degradation in a Drosophila model of amyotrophic lateral sclerosis. Chaplot K, et al. Dis Model Mech, 2019 Feb 7. PMID 30635270, Free PMC Article
    3. Protein phosphorylation changes reveal new candidates in the regulation of egg activation and early embryogenesis in D. melanogaster. Krauchunas AR, et al. Dev Biol, 2012 Oct 1. PMID 22884528, Free PMC Article
    4. A genetic interaction map of cell cycle regulators. Billmann M, et al. Mol Biol Cell, 2016 Apr 15. PMID 26912791, Free PMC Article
    5. Identification of genes that promote or inhibit olfactory memory formation in Drosophila. Walkinshaw E, et al. Genetics, 2015 Apr. PMID 25644700, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in regulation of mitotic cell cycle spindle assembly checkpoint IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of anaphase-promoting complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG15237-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      6809044..6809766 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136394.4 → NP_610238.2  uncharacterized protein Dmel_CG15237 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610238.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V665
      Conserved Domains (1) summary
      pfam15243
      Location:6 → 91
      ANAPC15; Anaphase-promoting complex subunit 15
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4V665 Q4V665

    Gene LinkOut

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