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    CG5002 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37025, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG5002provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034275
    Locus tag
    Dmel_CG5002
    See related
    AllianceGenome:FB:FBgn0034275
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG5002
    Summary
    Predicted to enable sulfate transmembrane transporter activity. Predicted to be involved in chloride transmembrane transport and sulfate transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including adult head; clypeo-labral primordium; dorsal apodeme anlage; dorsal ectoderm anlage; and embryonic/larval spiracle primordium. Orthologous to human SLC26A11 (solute carrier family 26 member 11). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG5002 in Genome Data Viewer
    Location:
    54E8-54E8; 2-84 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17750293..17753214)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13637798..13640719)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Ionotropic receptor 54a Neighboring gene subito Neighboring gene uncharacterized protein Neighboring gene Sarcosine dehydrogenase Neighboring gene HLH54F

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Ion and solute transport by Prestin in Drosophila and Anopheles. Hirata T, et al. J Insect Physiol, 2012 Apr. PMID 22321763, Free PMC Article
    2. Polycomb mediates Myc autorepression and its transcriptional control of many loci in Drosophila. Goodliffe JM, et al. Genes Dev, 2005 Dec 15. PMID 16357214, Free PMC Article
    3. Using the P[wHy] hybrid transposable element to disrupt genes in region 54D-55B in Drosophila melanogaster. Mohr SE, et al. Genetics, 2002 Sep. PMID 12242231, Free PMC Article
    4. Genes encoding novel secreted and transmembrane proteins are temporally and spatially regulated during Drosophila melanogaster embryogenesis. Zúñiga A, et al. BMC Biol, 2009 Sep 22. PMID 19772636, Free PMC Article
    5. Isolation of a natural DNA virus of Drosophila melanogaster, and characterisation of host resistance and immune responses. Palmer WH, et al. PLoS Pathog, 2018 Jun. PMID 29864164, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables sulfate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in chloride transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sulfate transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG5002-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      17750293..17753214
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137418.3 → NP_611262.1  uncharacterized protein Dmel_CG5002 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611262.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K4I4
      Related
      FBpp0088515
      Conserved Domains (3) summary
      COG0659
      Location:36 → 564
      SUL1; Sulfate permease or related transporter, MFS superfamily [Inorganic ion transport and metabolism]
      cl00604
      Location:469 → 544
      STAS; Sulphate Transporter and Anti-Sigma factor antagonist domain found in the C-terminal region of sulphate transporters as well as in bacterial and archaeal proteins involved in the regulation of sigma factors
      cl23746
      Location:103 → 385
      HCO3_cotransp; HCO3- transporter family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7K4I4 Q7K4I4

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