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    CG31549 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40689, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG31549provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051549
    Locus tag
    Dmel_CG31549
    See related
    AllianceGenome:FB:FBgn0051549
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG11005; Dmel\CG31549
    Summary
    Predicted to enable estradiol 17-beta-dehydrogenase [NAD(P)+] activity and testosterone 17-beta-dehydrogenase (NADP+) activity. Is expressed in adult head and organism. Orthologous to human HSD17B14 (hydroxysteroid 17-beta dehydrogenase 14). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG31549 in Genome Data Viewer
    Location:
    83B7-83B7; 3-47.5 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (5632192..5633321)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (1457914..1459043)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Ribosomal protein L13A Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Developmental defects by antisense-mediated inactivation of micro-RNAs 2 and 13 in Drosophila and the identification of putative target genes. Boutla A, et al. Nucleic Acids Res, 2003 Sep 1. PMID 12930946, Free PMC Article
    2. Quantitative Proteomic Analyses of Molecular Mechanisms Associated with Cytoplasmic Incompatibility in Drosophila melanogaster Induced by Wolbachia. Yuan LL, et al. J Proteome Res, 2015 Sep 4. PMID 26220534
    3. The 5'-3' exoribonuclease Pacman (Xrn1) regulates expression of the heat shock protein Hsp67Bc and the microRNA miR-277-3p in Drosophila wing imaginal discs. Jones CI, et al. RNA Biol, 2013 Aug. PMID 23792537, Free PMC Article
    4. A pupal transcriptomic screen identifies Ral as a target of store-operated calcium entry in Drosophila neurons. Richhariya S, et al. Sci Rep, 2017 Feb 14. PMID 28195208, Free PMC Article
    5. Genome-wide features of neuroendocrine regulation in Drosophila by the basic helix-loop-helix transcription factor DIMMED. Hadžić T, et al. Nucleic Acids Res, 2015 Feb 27. PMID 25634895, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables estradiol 17-beta-dehydrogenase [NAD(P)+] activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables testosterone 17-beta-dehydrogenase (NADP+) activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG31549-PA
    CG31549-PB
    NP_001262292.1
    NP_730972.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      5632192..5633321
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_169083.1 → NP_730972.2  uncharacterized protein Dmel_CG31549, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730972.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SX57, Q9VNF2
      Related
      FBpp0078356, FBtr0078707
      Conserved Domains (2) summary
      PRK07231
      Location:4 → 251
      fabG; 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional
      cl21454
      Location:4 → 254
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    2. NM_001275363.1 → NP_001262292.1  uncharacterized protein Dmel_CG31549, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262292.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SX57, Q9VNF2
      Conserved Domains (2) summary
      PRK07231
      Location:4 → 251
      fabG; 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional
      cl21454
      Location:4 → 254
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SX57 Q8SX57

    Gene LinkOut

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