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    Syx6 Syntaxin 6 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40373, updated on 9-Dec-2024

    Summary

    Official Symbol
    Syx6provided by FlyBase
    Official Full Name
    Syntaxin 6provided by FlyBase
    Primary source
    FLYBASE:FBgn0037084
    Locus tag
    Dmel_CG7736
    See related
    AllianceGenome:FB:FBgn0037084
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG7736; CT23545; Dm Syx6; Dmel\CG7736; DmSyx6; SYN6; Syx; syx6; SYX6/10
    Summary
    Predicted to enable SNAP receptor activity and SNARE binding activity. Predicted to be involved in several processes, including retrograde transport, endosome to Golgi; synaptic vesicle docking; and vesicle fusion. Predicted to be located in plasma membrane. Predicted to be part of SNARE complex. Predicted to be active in synaptic vesicle membrane. Is expressed in embryonic brain; larval nervous system; larval ventral nerve cord; and organism. Orthologous to several human genes including STX10 (syntaxin 10). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Syx6 in Genome Data Viewer
    Location:
    47D7-47E1; 2-64 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (11219539..11222480)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (7107044..7109985)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene schnurri Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene menage a trois Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables SNAP receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables SNAP receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables SNAP receptor activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    enables SNARE binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in Golgi vesicle transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in retrograde transport, endosome to Golgi IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in synaptic vesicle docking ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in vesicle docking IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in vesicle fusion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of SNARE complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    located_in plasma membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    is_active_in synaptic vesicle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    syntaxin 6
    Names
    CG7736-PB
    CG7736-PD
    CG7736-PE
    Syx6-PB
    Syx6-PD
    Syx6-PE
    syntaxin

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      11219539..11222480
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_206093.3NP_995815.1  syntaxin 6, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_995815.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86P32
      Conserved Domains (1) summary
      cd15851
      Location:137202
      SNARE_Syntaxin6; SNARE motif of syntaxin 6
    2. NM_206092.3NP_995814.1  syntaxin 6, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_995814.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5BI25, Q7JRF1
      Conserved Domains (2) summary
      cd15851
      Location:234299
      SNARE_Syntaxin6; SNARE motif of syntaxin 6
      cd21443
      Location:5103
      SNARE_NTD_STX6_STX10; N-terminal domain of syntaxin-6, syntaxin-10, and similar proteins
    3. NM_206094.3NP_995816.1  syntaxin 6, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_995816.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5BI25, Q7JY00
      Conserved Domains (2) summary
      cd15851
      Location:250315
      SNARE_Syntaxin6; SNARE motif of syntaxin 6
      pfam09177
      Location:29115
      Syntaxin-6_N; Syntaxin 6, N-terminal