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    CG13369 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31007, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG13369provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0025640
    Locus tag
    Dmel_CG13369
    See related
    AllianceGenome:FB:FBgn0025640
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG13369; EG:115C2.1
    Summary
    Predicted to enable ribokinase activity. Predicted to be involved in D-ribose metabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be active in cytosol. Orthologous to human RBKS (ribokinase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG13369 in Genome Data Viewer
    Location:
    1B12-1B12; 1-0 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (623468..624765)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (517501..518798)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45474 Neighboring gene uncharacterized protein Neighboring gene Vacuolar protein sorting 37A Neighboring gene long non-coding RNA:CR45475 Neighboring gene uncharacterized protein Neighboring gene Histone H4 transcription factor Neighboring gene Ribosomal protein L36

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sensitivity of the distribution of mutational fitness effects to environment, genetic background, and adaptedness: a case study with Drosophila. Wang AD, et al. Evolution, 2014 Mar. PMID 24206451
    2. Kinome-Wide RNAi Screen Uncovers Role of Ballchen in Maintenance of Gene Activation by Trithorax Group in Drosophila. Khan MHF, et al. Front Cell Dev Biol, 2021. PMID 33748127, Free PMC Article
    3. Dietary switch reveals fast coordinated gene expression changes in Drosophila melanogaster. Whitaker R, et al. Aging (Albany NY), 2014 May. PMID 24864304, Free PMC Article
    4. Genetic Basis of Increased Lifespan and Postponed Senescence in Drosophila melanogaster. Parker GA, et al. G3 (Bethesda), 2020 Mar 5. PMID 31969430, Free PMC Article
    5. Cross-species genetic screens to identify kinase targets for APP reduction in Alzheimer's disease. Huichalaf CH, et al. Hum Mol Genet, 2019 Jun 15. PMID 30753434, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ribokinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in D-ribose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG13369-PA
    NP_569850.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      623468..624765
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130494.4 → NP_569850.1  uncharacterized protein Dmel_CG13369 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_569850.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O77425
      Related
      FBpp0070110
      Conserved Domains (1) summary
      cd01174
      Location:6 → 303
      ribokinase; Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O77425 O77425

    Gene LinkOut

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