U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG9701 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39872, updated on 17-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG9701provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036659
    Locus tag
    Dmel_CG9701
    See related
    AllianceGenome:FB:FBgn0036659
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG9701; Dmel_CG9701; klotho
    Summary
    Predicted to enable beta-glucosidase activity. Predicted to be involved in carbohydrate metabolic process. Is expressed in embryonic proventriculus and gastric caecum. Human ortholog(s) of this gene implicated in congenital lactase deficiency; coronary artery disease; intracranial embolism; and spondylosis. Orthologous to several human genes including LCTL (lactase like). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG9701 in Genome Data Viewer
    Location:
    73C2-73C2; 3-44 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (16733546..16739364)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (16726646..16732464)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Peptidoglycan recognition protein SB1 Neighboring gene Dead box protein 73D Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46214

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Transporters and tubule crystals in the insect Malpighian tubule. Reynolds CJ, et al. Curr Opin Insect Sci, 2021 Oct. PMID 34044181, Free PMC Article
    2. Evidence for involvement of the alcohol consumption WDPCP gene in lipid metabolism, and liver cirrhosis. O'Farrell F, et al. Sci Rep, 2023 Nov 23. PMID 37996473, Free PMC Article
    3. Age-dependent changes in the transcription profile of long-lived Drosophila over-expressing glutamate cysteine ligase. Radyuk SN, et al. Mech Ageing Dev, 2012 Jun. PMID 22579812
    4. Regional specialization, polyploidy, and seminal fluid transcripts in the Drosophila female reproductive tract. Thayer RC, et al. Proc Natl Acad Sci U S A, 2024 Oct 29. PMID 39453739,
    5. Flying Together: Drosophila as a Tool to Understand the Genetics of Human Alcoholism. Lathen DR, et al. Int J Mol Sci, 2020 Sep 11. PMID 32932795, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables beta-glucosidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables hydrolase activity, hydrolyzing O-glycosyl compounds IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG9701-PA
    NP_648918.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      16733546..16739364
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140661.3 → NP_648918.1  uncharacterized protein Dmel_CG9701 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648918.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SZX2, Q9VV98
      Related
      FBpp0075080
      Conserved Domains (1) summary
      cl23725
      Location:22 → 492
      Glyco_hydro_1; Glycosyl hydrolase family 1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VV98 Q9VV98

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous