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    CG4318 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32266, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4318provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030455
    Locus tag
    Dmel_CG4318
    See related
    AllianceGenome:FB:FBgn0030455
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4318
    Summary
    Predicted to enable DNA-binding transcription factor activity and transcription cis-regulatory region binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in germline cell. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4318 in Genome Data Viewer
    Location:
    11E1-11E1; 1-42 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (13153461..13154924, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (13047494..13048957, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene small non-coding RNA 204 Neighboring gene uncharacterized protein Neighboring gene Major Facilitator Superfamily Transporter 10 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Brahma associated protein 60kD

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Chigno/CG11180 and SUMO are Chinmo-interacting proteins with a role in Drosophila testes somatic support cells. Rinehart L, et al. PeerJ, 2024. PMID 38495765, Free PMC Article
    2. An RNA-interference screen in Drosophila to identify ZAD-containing C2H2 zinc finger genes that function in female germ cells. Shapiro-Kulnane L, et al. G3 (Bethesda), 2021 Jan 18. PMID 33561227, Free PMC Article
    3. ZAD-Domain Is Essential for Nuclear Localization of Insulator Proteins in Drosophila melanogaster. Zolotarev NA, et al. Acta Naturae, 2016 Jul-Sep. PMID 27795848, Free PMC Article
    4. Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila. Kasinathan B, et al. Elife, 2020 Nov 10. PMID 33169670, Free PMC Article
    5. A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila. Port F, et al. Elife, 2020 Feb 13. PMID 32053108, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables transcription cis-regulatory region binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4318-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      13153461..13154924 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132632.2 → NP_572860.2  uncharacterized protein Dmel_CG4318 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572860.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V709, Q9VYG4
      Conserved Domains (4) summary
      COG5048
      Location:179 → 236
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:155 → 175
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:5 → 64
      zf-AD; Zinc-finger associated domain (zf-AD)
      pfam13465
      Location:167 → 192
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VYG4 Q9VYG4

    Gene LinkOut

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