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    Pxd Peroxidase [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 2768671, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Pxdprovided by FlyBase
    Official Full Name
    Peroxidaseprovided by FlyBase
    Primary source
    FLYBASE:FBgn0004577
    Locus tag
    Dmel_CG3477
    See related
    AllianceGenome:FB:FBgn0004577
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG3477; Dmel\CG3477; DmPO; Dpxd; HPX1; PO
    Summary
    Enables peroxidase activity. Predicted to be involved in egg chorion assembly. Located in egg chorion. Is expressed in endochorion; follicle cell; and micropyle. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Pxd in Genome Data Viewer
    Location:
    89E8-89E9; 3-59 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (17014576..17027987)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (12840298..12853709)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Immune-regulated catalase Neighboring gene uncharacterized protein Neighboring gene Adenylosuccinate lyase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular characterization of a putative peroxidase gene of Drosophila melanogaster. Ng SW, et al. Biochim Biophys Acta, 1992 Dec 29. PMID 1482687
    2. A new peroxinectin-like gene preferentially expressed during oogenesis and early embryogenesis in Drosophila melanogaster. Vázquez M, et al. Dev Genes Evol, 2002 Dec. PMID 12459925
    3. Beyond the mouse model: using Drosophila as a model for sperm interaction with the female reproductive tract. Heifetz Y, et al. Theriogenology, 2010 Apr 1. PMID 20015541
    4. Curly Encodes Dual Oxidase, Which Acts with Heme Peroxidase Curly Su to Shape the Adult Drosophila Wing. Hurd TR, et al. PLoS Genet, 2015 Nov. PMID 26587980, Free PMC Article
    5. A Quantitative Genomic Approach for Analysis of Fitness and Stress Related Traits in a Drosophila melanogaster Model Population. Duun Rohde P, et al. Int J Genomics, 2016. PMID 27274984, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peroxidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables peroxidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables peroxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in egg chorion assembly IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in response to oxidative stress IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in egg chorion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    peroxidase
    Names
    CG3477-PA
    CG3477-PB
    CG3477-PC
    Pxd-PA
    Pxd-PB
    Pxd-PC
    NP_001163633.1
    NP_001262654.1
    NP_996223.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      17014576..17027987
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_206501.3 → NP_996223.1  peroxidase, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996223.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q01603, Q6IJW8, Q7KSF9
      UniProtKB/TrEMBL
      E1JIN0
      Conserved Domains (2) summary
      cd09823
      Location:260 → 638
      peroxinectin_like; peroxinectin_like animal heme peroxidases
      pfam03098
      Location:105 → 643
      An_peroxidase; Animal haem peroxidase

    2. NM_001275725.1 → NP_001262654.1  peroxidase, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262654.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KHM9
      Conserved Domains (2) summary
      cd09823
      Location:258 → 636
      peroxinectin_like; peroxinectin_like animal heme peroxidases
      pfam03098
      Location:103 → 641
      An_peroxidase; Animal haem peroxidase

    3. NM_001170162.2 → NP_001163633.1  peroxidase, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163633.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q01603, Q6IJW8, Q7KSF9
      UniProtKB/TrEMBL
      E1JIN0
      Conserved Domains (2) summary
      cd09823
      Location:260 → 638
      peroxinectin_like; peroxinectin_like animal heme peroxidases
      pfam03098
      Location:105 → 643
      An_peroxidase; Animal haem peroxidase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KHM9 A0A0B4KHM9
    E1JIN0 E1JIN0
    Q01603.2 Q01603

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