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    CG32333 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38142, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG32333provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0052333
    Locus tag
    Dmel_CG32333
    See related
    AllianceGenome:FB:FBgn0052333
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cg32333; CG9137; CG9146; Dmel\CG32333
    Summary
    Predicted to be involved in cellular lipid metabolic process. Is expressed in antennal disc; eye disc; leg disc; and wing disc. Orthologous to human FAM135A (family with sequence similarity 135 member A) and FAM135B (family with sequence similarity 135 member B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG32333 in Genome Data Viewer
    Location:
    61F4-61F5; 3-0 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (1275956..1295699)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (1275956..1295699)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene triforce Neighboring gene Rabaptin-5-associated exchange factor for Rab5 Neighboring gene supercoiling factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic Variation and Potential for Resistance Development to the tTA Overexpression Lethal System in Insects. Knudsen KE, et al. G3 (Bethesda), 2020 Apr 9. PMID 32019873, Free PMC Article
    2. Functional genomic analysis of the 61D-61F region of the third chromosome of Drosophila melanogaster. Wei HC, et al. Genome, 2003 Dec. PMID 14663523
    3. EAST Organizes Drosophila Insulator Proteins in the Interchromosomal Nuclear Compartment and Modulates CP190 Binding to Chromatin. Golovnin A, et al. PLoS One, 2015. PMID 26489095, Free PMC Article
    4. New components of Drosophila leg development identified through genome wide association studies. Grubbs N, et al. PLoS One, 2013. PMID 23560084, Free PMC Article
    5. A Superfamily-wide Activity Atlas of Serine Hydrolases in Drosophila melanogaster. Kumar K, et al. Biochemistry, 2021 Apr 27. PMID 33827210, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in lipid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG32333-PA
    CG32333-PB
    CG32333-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      1275956..1295699
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001274317.1 → NP_001261246.1  uncharacterized protein Dmel_CG32333, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261246.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PGQ5
      Conserved Domains (3) summary
      COG0596
      Location:1223 → 1447
      MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]
      pfam05057
      Location:1227 → 1422
      DUF676; Putative serine esterase (DUF676)
      pfam12394
      Location:150 → 226
      DUF3657; Protein of unknown function (DUF3657)

    2. NM_167865.3 → NP_728588.1  uncharacterized protein Dmel_CG32333, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728588.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W0I1
      Related
      FBpp0072556
      Conserved Domains (3) summary
      COG0596
      Location:1213 → 1437
      MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]
      pfam05057
      Location:1217 → 1412
      DUF676; Putative serine esterase (DUF676)
      pfam12394
      Location:150 → 226
      DUF3657; Protein of unknown function (DUF3657)

    3. NM_001014555.2 → NP_001014555.1  uncharacterized protein Dmel_CG32333, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001014555.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MRM7
      Conserved Domains (1) summary
      pfam12394
      Location:150 → 226
      DUF3657; Protein of unknown function (DUF3657)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PGQ5 M9PGQ5
    Q8MRM7 Q8MRM7
    Q9W0I1 Q9W0I1

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